Results 111 to 120 of about 136,147 (290)

Three passive arm-support exoskeletons have inconsistent effects on muscle activity, posture, and perceived exertion during diverse simulated pseudo-static overhead nutrunning tasks

, 2023
Aanuoluwapo Ojelade, Wallace Morris, Sunwook Kim, Denean Kelson, Divya Srinivasan, Marty Smets, Maury A. Nussbaum   +6 more
openalex   +2 more sources

The effect of caffeine mouth rinse on self-paced cycling performance [PDF]

, 2014
The aim of the study was to determine whether caffeine mouth rinse would improve 30 min self-paced cycling trial. Twelve healthy active males (age 20.5±0.7 years, mass 87.4±18.3 kg) volunteered for the study.
Barry, G., Bolton, J, Bottoms, Lindsay, Hurst, Howard Thomas, Lynch, F, Scriven, A, Shone, Z., Sinclair, Jonathan Kenneth, Vercoe, L.   +8 more
core   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

The effect of thermal insulation pads on heat flux, physical effort and perceived exertion during endurance exercise in cool environments

Fashion and Textiles, 2018
To determine the effects of thermal insulation pads on clothing surface temperature, physical effort and perceived exertion during endurance exercise in cool environments two different pants (PCOOL, PINSUL) were designed: PCOOL (Insulation: 0.055 clo ...
Sebastian Wenger, Robert Csapo, Michael Hasler, Hannes Gatterer, Tom Wright, Werner Nachbauer   +5 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Quantifying physical activity across the midlife: Does consideration of perceived exertion matter?

, 2022
Kelly R. Ylitalo, Carrie Karvonen‐Gutierrez, Minsuk Oh, Barbara Sternfeld, James D. Stamey, Kelley Pettee Gabriel   +5 more
openalex   +1 more source

Pain Response after Maximal Aerobic Exercise in Adolescents across Weight Status [PDF]

, 2015
Introduction Pain reports are greater with increasing weight status, and exercise can reduce pain perception. It is unknown, however, whether exercise can relieve pain in adolescents of varying weight status.
Bement, Marie K. Hoeger, Danduran, Michael E., Hunter, Sandra K., Stolzman, Stacy   +3 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study

, 2021
Simon Nichols, Buket Engin, Sean Carroll, John Buckley, Lee Ingle   +4 more
openalex   +2 more sources

The effect of low volume sprint interval training in patients with non-alcoholic fatty liver disease [PDF]

, 2017
Objectives: Exercise is an important part of disease management in patients with non-alcoholic fatty liver disease (NAFLD), but adherence to current exercise recommendations is poor.
Babraj, John A., Dillon, John, MacLean, Catriona, Vollaard, Niels B. J.   +3 more
core   +5 more sources