Results 91 to 100 of about 4,456,923 (313)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Interfaces of Student Lifestyle and Perceived Stress

Baltic Journal of Sport and Health Sciences, 2020
Background. It is becoming obvious that healthy lifestyle of students in higher education institutions is an important factor contributing to the duration of their professional career as well as for general health (Bolotin & Bakayev, 2015). High academic expectations increase tension and pose a threat to physical and mental health of students ...
Vizbaraitė, Daiva, Stanionytė, Gintarė, Ossowsky, Zbigniew   +2 more
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Perceived stress in occupational therapy students

Occupational Therapy International, 2008
AbstractThe purpose of this study was to examine perceived stress of entry‐level master's occupational therapy (OT) students enrolled at a Texas university. A total of 29 students including nine men and 20 women participated in the study. Questionnaires and interviews were used for data collection.
Teresa A, Pfeifer, Peter L, Kranz, Angela E, Scoggin   +2 more
openaire   +3 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

An exploration of stress and its perception in childhood [PDF]

, 1997
This research explores the concept of stress as it is perceived by children and builds a paradigm of this perception. The thesis argues that a cognitive paradigm is useful in understanding the stress process but seems incomplete without an ...
Robson, Margaret Anne, Robson, M.A.
core  

Perceived stress and biological risk: is the link stronger in Russians than in Taiwanese and Americans?

, 2013
Allostatic load theory implies a relationship between exposure to psychological stress and multi- system physiological dysregulation. We used data from population-based samples in Russia (Moscow), Taiwan, and the United States (US)—which are likely to ...
Vaupel, James W, Glei, Dana A, Shkolnikov, Vladimir M, Jdanov, Dmitri, Goldman, Noreen, Weinstein, Maxine, Shkolnikova, Maria   +6 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Corelation of Perceived Social Support and Psychological Hardness with Perceived Stress and Aggression in Retired Veterans

طب جانباز, 2018
Aims: The purpose of this study was to investigate the role of perceived social support and psychological hardness in perceived stress and aggression of retired veterans. Instrument and Methods: This study is a descriptive correlational which was done in
L. Ebrahimi, F. Moradi
doaj