Results 101 to 110 of about 1,873,432 (279)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Does Perceived Usefulness, Perceived Ease of Use, And Perceived Risk Has Influence on Intention To Use E-Wallet?

open access: yesVISA: Journal of Vision and Ideas
Aligned with technological advancements, digital-based financial services have undergone development, leading to continuous changes and innovations in online payment methods. Among these innovations is the emergence of electronic wallets, known as electronic wallet, (e-wallets) as a non-cash payment tool.
null Tan Christabel Michaela Devina   +1 more
openaire   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Exploring the Impact of Perceived Usefulness on Behavioral Intention: The Mediating Role of Trust

open access: yesJurnal Manajemen Universitas Bung Hatta
The purpose of this study is to ascertain how perceived usefulness affects on behavioral intention, with trust acting as a mediating factor in the Shopeepay e-wallet service in Padang.
Irda Irda   +3 more
doaj  

An extension of the technology acceptance model for understanding travelers' adoption of variable message signs.

open access: yesPLoS ONE, 2019
Understanding travelers' acceptance of Advanced Traveler Information Systems (ATIS) is crucial to the implementation of Intelligent Transportation Systems (ITS) capable of mitigating traffic congestion and improving network performance.
El Bachir Diop   +2 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Factors Influencing Telemedicine Adoption Among Healthcare Professionals in Geriatric Medical Centers: A Technology Acceptance Model Approach

open access: yesBehavioral Sciences
Background: Telemedicine has gained significance, especially during the COVID-19 pandemic, offering remote healthcare solutions. However, its adoption in geriatric medical centers (GMCs) remains limited. Understanding the factors influencing telemedicine
Tammy Porat-Packer   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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