Results 91 to 100 of about 765,885 (315)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Control-value appraisals, achievement emotions and English performance in Chinese middle school students

open access: yesActa Psychologica
Guided by the control-value theory of achievement emotions, this study examined the relations between control-value appraisals, achievement emotions and English performance in Chinese middle school students, with a focus on the predictive effects of ...
Meihua Liu   +3 more
doaj   +1 more source

Customers’ perceived value towards the service in Islamic banking: Confirmatory factor analysis

open access: yesJournal of Economics, Business & Accountancy Ventura, 2015
This study attempts to analyze the dimensionality of the concept of perceived value in Islamic banking sector, adapting to six dimensions of the GLOVAL scale and one additional dimension that is spiritual as measurement of perceived value to Islamic ...
Suryani Suryani
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Conceptualising customer value in a leisure service setting: value is in the eye of the beholder.

open access: yes, 2013
Currently there is little research that considers value or value creation from a sport and physical activity context or from the participant’s perspective.
Kearns, PJ
core  

The Impact of Product Perceived Value on Green Furniture Purchase Intention: The Mediating Role of Customer Value

open access: yesBioResources
Although consumer interest in green furniture is growing, existing research has seldom examined the underlying psychological mechanisms driving such behavior.
Tao Shi, Shulan Yu, Lu Zhang, DongLin Li
doaj  

The effect of perceived value on behavioural intentions

open access: yesPressacademia, 2017
Purpose- This study investigates the relation between perceived value and behavioural intentions in the intercity passenger transportation industry from a multidimensional point of view. It is expected to contribute to theory and practice through the conceptualisation of perceived value within the benefit and sacrifice components and revelation of the ...
Basaran, Umit, Aksoy, Ramazan
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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