Results 111 to 120 of about 765,885 (315)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Impacts of price and quality perceptions on individuals’ intention to participate in marathon events: Mediating role of perceived value

open access: yes, 2023
This study examines the relationships among perceived price, quality, and value and their impact on the intent to participate in marathon events. An online questionnaire survey was administered to individuals who had participated in a marathon within the
Wang, F. J.;Hsiao, C. H.;Shih, W. H.;Chiu, W
core  

The Influence of Perceived Value on Customer Loyalty in Slovenian Hotel Industry [PDF]

open access: yesTurizam, 2008
Perceived value has an enormous influence on customer behavior, because it influences his decisions on product choice, purchase intentions and repeat purchasing. Most frequently it appears in connection with quality and customer satisfaction. The purpose
Tadeja Krasna
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Making sense of higher education: students as consumers and the value of the university experience

open access: yes, 2014
In the global university sector competitive funding models are progressively becoming the norm, and institutions/courses are frequently now subject to the same kind of consumerist pressures typical of a highly marketised environment.
Woodall, T, Hiller, A, Resnick, S
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

A Study of Product Involvement Perceived Value and Purchase Intention for Consumers to Organic Food.

open access: yes, 2009
[[abstract]]With the social-economic changes in the safety of modern diet has become the focus of public concern, and market organic food itself will become a new favorite.The purpose of this study is that consumers of organic food Product Involvement ...
Kai-Chi Chang
core  

Investigating the Effect of Risk, Value, and Price Consciousness on Willingness to Purchase Gray Market Goods in Kerman Province

open access: yesتحقیقات بازار یابی نوین, 2011
In the scope of international marketing, gray market has attracted too much attention in recent years. On this basis, the following study examines the factors influencing consumer willingness to purchase gray market goods in Kerman Province.
A. mollahosseini, B. jabbarzadeh
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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