Results 181 to 190 of about 765,885 (315)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Effectiveness of design thinking pedagogy in SCCT-based career guidance: Students' career decision-making self-efficacy and perceived value. [PDF]

PLoS One
Cai Y, Arumugam N, Chen Y.
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Variations in the perceived value of anti-SARS-CoV-2 therapeutics based on physicians' clinical backgrounds. [PDF]

Sci Rep
Hagiwara A, Komiya K, Shindo Y, Takamatsu K, Nishimura N, Takechi Y, Ichihara E, Takazono T, Izumi S, Gotoh S, Sakao S, Izumo T, Yamamoto K, Yatera K, Kakeya H, Shibata Y, Tomii K, Sagara H, Sasaki Y, Hirai T, Yokoyama A, Mukae H, Ogura T.   +22 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Service quality as a driver of perceived value satisfaction and revisit intention in Indonesia. [PDF]

Sci Rep
Noviyani A, Viwattanakulvanid P.
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Flow as the mediating mechanism in marathon events: connecting event quality, motivation, and self-efficacy to perceived value and performance. [PDF]

Front Sports Act Living
Wu T, Kim S, Oh T.
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

DR. INFO at the Point of Care: A Prospective Pilot Study of Physician-Perceived Value of an Agentic Artificial Intelligence Clinical Assistant. [PDF]

Cureus
Corga da Silva R, Romano M, Mendes T, Isidoro M, Ravichandran S, Kumar S, Van der Heijden M, Fail O, Emmanuel Gnanapragasam V.   +8 more
europepmc   +1 more source