Results 221 to 230 of about 765,885 (315)

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Cultural distortion risk and tourist loyalty at silk road heritage: The mediating roles of perceived value and satisfaction. [PDF]

PLoS One
Wu K, Su L, Zhang S, Yang S, Xing A, Zhou J.   +5 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Research on the impact mechanism of Green Emotional Involvement on Consumer Engagement Behavior: the chain mediating roles of Perceived Authenticity and Perceived Value. [PDF]

Front Psychol
Yang Y, Su Q.
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Telemedicine in epilepsy care: A Nationwide survey by the Italian Chapter of the International League Against Epilepsy (LICE) on adoption, barriers, and perceived value. [PDF]

Epilepsia Open
Brigo F, Assenza G, Dono F, Duca M, Lanzone J, Lo Barco T, Licchetta L, Spagnoli C, Tassi L, Trivisano M, Mecarelli O.   +10 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

How Does Perceived Value Influence Functional Snack Consumption Intention? An Empirical Analysis Based on Generational Differences. [PDF]

Foods
Chen X, Zhang XE, Yin J, Chen J, Lin H.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

The effectiveness and perceived value of feedback used in cardiac arrest simulation education: a mixed-method systematic review. [PDF]

Scand J Trauma Resusc Emerg Med
Vella R, Baker E, Akerjordet K, Thyer L.
europepmc   +1 more source