Results 131 to 140 of about 5,164,002 (344)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Veterans’ Satisfaction analysis of Disability rating commission

open access: yesطب جانباز, 2010
Introduction: Medical disability rating Commission is the only way through Iranian Veterans and War Victims’ Organization and allocation of all facilities is related to its permission.
E. Modirian, A.H. Eskandari
doaj  

Paid Leave in Private Industry Over the Past 20 Years [PDF]

open access: yes, 2013
[Excerpt] Paid leave was the most prevalent employee benefit provided by employers in private industry throughout the United States in 2012. Eighty-four percent of private industry workers received vacation, holiday, or personal leave.
Van Giezen, Robert W
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Estrogen receptor assay on breast cancer microsamples: Implications of percent carcinoma estimation [PDF]

open access: bronze, 1982
Johannes P. van Netten   +6 more
openalex   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Strategies for Successfully Marketing and Stabilizing the Occupancy of Mixed-Income/Mixed-Race Properties: A Case Study of Spanish Oaks in Jacksonville, Florida [PDF]

open access: yes, 2005
Spanish Oaks is a late 1960s garden apartment development in the Arlington section of Jacksonville, Florida. Originally built as market-rate rental housing, Spanish Oaks entered the inventory of the Resolution Trust Corporation (RTC) after the original ...
Jill Khadduri
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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