Results 51 to 60 of about 5,164,002 (344)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Estimating Percent Residue Cover Using the Line-Transect Method [PDF]
, 2009 Leaving crop residue on the soil surface is one of the easiest and most cost-effective methods of reducing soil erosion. Research in Nebraska and other midwestern states has shown that leaving as little as 20 percent of the soil surface covered with crop
Jasa, Paul J., Shelton, David P.
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
STUDY ON THE HERITABILITY OF MILK PRODUCTION IN A LINE OF HOLSTEIN FREISE [PDF]
AgroLife Scientific Journal, 2015 Livestock genetical structure improvement from one generation to another request, among others, the knowledge of their genetical parameters. The guidance of livestock genetical structure involves the knowledge of the share caused by genetical and ...
Tomiţa DRAGOTOIU +5 more
doaj
Is the Unemployment Rate in Sweden Really 17 Percent? [PDF]
, 2007 This report finds the U.S. unemployment rate would be 13 percent using a methodology frequently cited in critiques of Sweden's "real" unemployment rate. The McKinsey Global Institute's calculations of Sweden's "de-facto" unemployment rate as 17 percent -
John Schmitt
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Evaporative segregation in 80 percent Ni-20 percent Cr and 60 percent Fe-40 percent Ni alloys [PDF]
The phenomenon of evaporative segregation in binary alloys has been investigated through a study of some experimental evaporation data relating to the Ni-Cr and Ni-Fr systems.
Gupta, K. P. +2 more
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source