Results 101 to 110 of about 804,363 (217)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Leasing and Secondary Markets: Theory and Evidence from Commercial Aircraft [PDF]
I construct a dynamic model of transactions in used capital to understand the role of leasing when trading is subject to frictions. Firms trade assets to adjust their productive capacity in response to shocks to profitability.
Gavazza, Alessandro
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Auctions vs negotiations in public procurement: which works better? [PDF]
Public agencies rely on two key modes to procure goods and services: auctions and direct negotiations. The relative advantages of these two modes are still imperfectly understood.
Armin Schmutzler, Rafael Lalive
core
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Measuring the Efficiency of Selected Hotels in Tehran: A DEA Approach [PDF]
پژوهشهای اقتصادی, 2008 Hotels are fundamental elements of tourism industry and provide various services for tourists. Moreover, hotels development has an important impact on tourism industry development.
mahmoud khataei +2 more
doaj
Who's Winning the Clean Energy Race? Growth, Competition and Opportunity in the World's Largest Economies: G-20 Clean Energy Factbook [PDF]
, 2010 Provides an overview of trends in the global clean energy economy, profiles G-20 countries' clean energy investments, and explores domestic policies to reduce global warming and incentivize the use of renewable energy that support competitive ...
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Improved estimator for the estimation of sensitive variable using ORRT models
Research in StatisticsIn this study, we concern with the improved estimation of sensitive variable when there is non-response and measurement error on sensitive variable but the auxiliary variable is non sensitive in nature.
Sunil Kumar, Chanda Rani
doaj +1 more source
Wind tunnel performance of four energy efficient propellers designed for Mach 0.8 cruise [PDF]
Several advanced aerodynamic and acoustic concepts were investigated in recent wind tunnel tests performed in the NASA-Lewis Research Center 8x6 foot wind tunnel.
Blaha, B. J. +2 more
core +1 more source