ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu +10 more
wiley +1 more source
Gross efficiency is a measure of the ability to convert stored energy into power and is included as an important element in the majority of performance models.
Brown, M., Coleman, D., Saunders, S.
core
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang +13 more
wiley +1 more source
Calibration and count rate performance of NaI(Tl) gamma counters for quantifying the activity <sup>89</sup>Zr radiopharmaceuticals. [PDF]
Silosky M.
europepmc +1 more source
Some Determinants of Intermediate Local Governments' Spending Efficiency: The Case of French Départements [PDF]
Efforts undertaken by France to restructure the allocation of governmental competencies increased the importance of subnational governments by transferring additional tasks.
Stefan Seifert, Maria Nieswand
core
Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli +13 more
wiley +1 more source
Membrane-Coated Iron Oxide (Fe<sub>3</sub>O<sub>4</sub>) Nanoparticles Encapsulating Dacarbazine Suppress B16F10 Melanoma Cell Activity in vitro and in a Subcutaneous Mouse Model. [PDF]
Ding H +6 more
europepmc +1 more source
AN EFFICIENCY ANALYSIS OF CATTLE BACKGROUNDING IN KANSAS [PDF]
Efficiency measures can be used to generate inferences about the future direction of the industry and determine factors that may influence the structure. This study evaluated relative efficiencies of Kansas backgrounding operations. Farms that engaged in
Langemeier, Michael R., Gow, Laura R.
core
Anticoagulation Treatment Response Among Phenotypic ESUS Clusters: Evidence From CASPR
ABSTRACT Objective To evaluate treatment effect heterogeneity across phenotypic clusters of patients with cryptogenic embolic stroke using causal inference methods. Methods From a retrospective, multicenter cohort of patients with cryptogenic embolic stroke, we estimated the treatment effect of anticoagulation versus antiplatelet therapy in patients ...
Elena Badillo Goicoechea +53 more
wiley +1 more source
Multitrophic dataset for multi-taxon abundance and richness estimations from biomass and nutrient energetics. [PDF]
Baach E, Dormann CF.
europepmc +1 more source

