Results 131 to 140 of about 69,628 (287)

Comparative Effectiveness of GLP‐1RAs, SGLT2is and DPP4is for Cardiovascular Outcomes in Type 2 Diabetes: An Empirically Calibrated Target Trial Emulation Study

Diabetes, Obesity and Metabolism, EarlyView.
Bingyu Zhang, Ting Zhou, Huilin Tang, Yiwen Lu, Dazheng Zhang, Jiajie Chen, Tianchu Lyu, Kai Zheng, David A. Asch, Yong Chen   +9 more
wiley   +1 more source

Phenotype Refinement Influences GWAS‐Implicated Variant Effect Sizes for Insomnia

Journal of Sleep Research, EarlyView.
ABSTRACT How phenotypes are measured, especially when relying on subjective reports, is an impediment to the utility of genome‐wide association studies (GWAS). This is a common problem in GWAS for sleep traits, as many sleep disturbances appear subjectively similar despite having distinct underlying pathophysiology.
Amber J. Zimmerman, Patrick Z. Liu, Brendan T. Keenan, Thomas G. Brooks, Struan F. A. Grant, Philip R. Gehrman, Ron C. Anafi, Allan I. Pack   +7 more
wiley   +1 more source

Broadband backscattering confocal microscopy enables label-free 3D live cell nanoscale sensitive imaging. [PDF]

Sci Adv
Coughlan MF, Zhang L, Perelman RT, Khan U, Zhang X, Upputuri PK, Zakharov YN, Qiu L, Perelman LT.   +8 more
europepmc   +1 more source

Association of GLP‐1 Receptor Agonists With Gastrointestinal and Liver Outcomes in Adults With Type 2 Diabetes: A Target Trial Emulation Study

Diabetes, Obesity and Metabolism, EarlyView.
Dazheng Zhang, Ying Lu, Xinyao Jian, Haoyuan Wang, Jacquelyn Hatch‐Stein, Ronen Stein, Jennifer Panganiban, Yong Chen   +7 more
wiley   +1 more source

When words fail us: An integrative review of innovative elicitation techniques for qualitative interviews

Medical Education, Volume 59, Issue 4, Page 382-394, April 2025.
Abstract Introduction Interviews are central to many qualitative studies in health professions education (HPE). However, researchers often struggle to elicit rich data and engage diverse participants who may find this strategy exclusionary. Elicitation techniques are strategies tailored to address these challenges, enhancing oral conversations through ...
Renate Kahlke, Lauren A. Maggio, Mark C. Lee, Sayra Cristancho, Kori LaDonna, Zahra Abdallah, Aakashdeep Khehra, Kushal Kshatri, Tanya Horsley, Lara Varpio   +9 more
wiley   +1 more source

Author Correction: Mitochondrial adaptor TRAK2 activates and functionally links opposing kinesin and dynein motors. [PDF]

Nat Commun
Fenton AR, Petruconis CR, Jongens TA, Holzbaur ELF.   +3 more
europepmc   +1 more source

Myths we tell ourselves about validity: A justice‐oriented reckoning in medical education

Medical Education, EarlyView.
Abstract Background Medical education has moved beyond debating whether objectivity in assessment is achievable, acknowledging that assessment is inherently subjective. Yet the pursuit of objectivity, through standardisation, bias reduction and statistical rigour, remains a cherished goal.
Hannah L. Kakara Anderson, Neera Jain, Benjamin Kinnear, Daniel C. West, Jennifer Randall   +4 more
wiley   +1 more source

Advancing Microcirculation Research in Advanced Heart Failure: The Case for Methodologic Consensus. [PDF]

JACC Adv
Greenwood JC, Wald JW, Schurr JW.
europepmc   +1 more source

The Role of torS and torT Transcription in Driving a Bet‐Hedging Strategy for Trimethylamine N‐Oxide Reductase Expression in Escherichia coli

Molecular Microbiology, EarlyView.
Low basal activity of divergent promoters driving transcription of the trimethylamine N‐oxide (TMAO) sensor TorT and kinase TorS is integral to an O2‐regulated bet‐hedging strategy for continued E. coli growth upon the onset of anaerobiosis. This, along with repression by IscR, promotes noise in the TorS to TorT ratio, which is critical for adaptation ...
Erin L. Mettert, Jeffrey N. Carey, Wilma Ross, Mark Goulian, Patricia J. Kiley   +4 more
wiley   +1 more source

Publisher Correction: Genome-wide association study of coronary flow reserve assessed by cardiac perfusion PET suggests a role for NF-κB pathway. [PDF]

Nat Cardiovasc Res
Venkatesh R, Cherlin T, Wayne N, Kumar R, Guare L, Singamneni VP, Irving B, Dudek S, Penn Medicine BioBank, Levin MG, Setia-Verma S, Guerraty MA.   +11 more
europepmc   +1 more source