Results 51 to 60 of about 120,930 (291)

Diagnostic Utility of Testing for Novel Murine Autoantibodies for Sjögren's Disease in the Rheumatology Outpatient Setting

Arthritis Care &Research, Accepted Article.
Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren's disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr, Michael D. George, Vatinee Y. Bunya, Nora Sandorfi, Mina Massaro‐Giordano, Frederick B. Vivino   +5 more
wiley   +1 more source

Flux de Hamilton-Ricci en varietats tridimensionals [PDF]

, 2007
Expliquem els treballs de Perelman, que ha resolt la conjectura de Thurston, i en particular la conjectura de Poincaré, mitjançant el flux de la curvatura de Ricci introduït per Hamilton.Here we explain the work of Perelman, who solved Thurston’s ...
Porti, Joan
core  

High‐Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

Advanced Materials, EarlyView.
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton, Ajay S. Thatte, Junchao Xu, Zhangyi Luo, Hannah C. Safford, Kelsey L. Swingle, Jenna Muscat‐Rivera, Michael Kegel, Xuexiang Han, Ryann A. Joseph, Amanda M. Murray, Hannah C. Geisler, Ricardo C. Whitaker, Lulu Xue, Roman Spektor, Jilian R. Melamed, Drew Weissman, Michael J. Mitchell   +17 more
wiley   +1 more source

METÁFORA Y ANALOGÍA EN UN SERVICIO DE INTELIGENCIA POLICIAL DE ARGENTINA

Metáfora, 2018
En el marco de estudio de la metáfora y la analogía planteado por Perelman (1970, 1978) y Perelman y Olbrechts-Tyteca (1989), el objetivo de este artículo es describir la construcción retórica de la Dirección de Inteligencia de Policía de la Provincia ...
María Alejandra Vitale
doaj   +1 more source

A Molecular Phylogeny of Living Primates

PLoS Genetics, 2011
Comparative genomic analyses of primates offer considerable potential to define and understand the processes that mold, shape, and transform the human genome.
P. Perelman, W. Johnson, C. Roos, H. Seuánez, J. Horvath, M. A. Moreira, B. Kessing, J. Pontius, M. Roelke, Y. Rumpler, M. Schneider, Artur Silva, S. O’Brien, J. Pecon-Slattery   +13 more
semanticscholar   +1 more source

Matrix Stiffness Governs Fibroblasts’ Regulation of Gingival Immune Homeostasis

Advanced Materials, EarlyView.
This study identifies a “mechano‐epigenetic” checkpoint in which matrix stiffness governs the immune responses of gingival fibroblasts. Using biomimetic hydrogels and human gingival explants, the studies revealed that restoring extracellular matrix stiffness actively suppresses inflammation via non‐canonical NF‐κB signaling and DNA methylation ...
Hardik Makkar, Nghi Tran, Yu‐Chang Chen, Kang I. Ko, Rebecca G. Wells, Kyle H. Vining   +5 more
wiley   +1 more source

¿ARGUMENTACIÓN O DEMOSTRACIÓN EN LA DECISIÓN JUDICIAL? UNA MIRADA EN EL ESTADO CONSTITUCIONAL

Revista de Derecho, 2009
El texto plantea el problema en torno a la decisión judicial correcta teniendo en cuenta dos líneas de discusión: primero, la diferenciación en torno a argumentar y demostrar, y segundo, el papel del juez con miras a lograr dicha corrección en el Estado ...
Javier Orlando Aguirre Román, Pedro Antonio García Obando, Ana Patricia Pabón Mantilla   +2 more
doaj  

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Advanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, Liam S. Chase, Drew Weissman, Jeremy B. Katzen, David B. Frank, Mariko L. Bennett, Oscar A. Marcos‐Contreras, Jacob W. Myerson, Vladimir R. Muzykantov, Sahily Reyes‐Esteves, Jacob S. Brenner   +24 more
wiley   +1 more source

Perelman's entropy on ancient Ricci flows [PDF]

, 2021
Zilu Ma, Yongjia Zhang
semanticscholar   +1 more source

Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination

Advanced Science, EarlyView.
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi, Colby J. Agostino, Jinwei Huang, Toshitha Kannan, Niklas Laenger, Jennifer Londregan, Katlyn Lederer, Michaela Helble, Nicole Bedanova, Cory Livingston, Ebony N. Gary, Madison McCanna, Marta Tarquis Medina, Rumi Habib, Ignacio Rodriguez Relaño, Ivan Maillard, Ami Patel, David Allman, Andrew Kossenkov, Amelia Escolano, Daniel W. Kulp, David. B. Weiner   +21 more
wiley   +1 more source