Results 51 to 60 of about 70,911 (284)
Optical Control of the Glucocorticoid Receptor Activity With a Photoswitchable Agonist
Angewandte Chemie, EarlyView.A photoswitchable glucocorticoid receptor agonist enables optical control of receptor activity, achieving picomolar potency and partial agonism that preferentially maintains anti‐inflammatory signaling over canonical transcriptional activation. ABSTRACT Glucocorticoids (GCs) are widely prescribed anti‐inflammatory agents whose clinical utility is ...
Zoe Sessions +8 more
wiley +2 more sources
Eye and Brain, 2022 Manzar Ashtari,1– 3 Mikhail Lipin,1,2 Michelle Duong,4 Gui-Shuang Ying,5 Yinxi Yu,5 Albert Maguire,1,2 Jean Bennett1,2 1Department of Ophthalmology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA; 2Department of ...
Ashtari M +6 more
doaj
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Sinonasal neuroendocrine carcinoma (SNEC) and sinonasal undifferentiated carcinoma (SNUC) are rare aggressive malignancies with no established prognostic markers. Because features of POU2F3+ small cell lung carcinomas have been identified in both tumors, we evaluated immunostaining for POU2F3, a tuft cell transcription factor, and ...
Nikolina Dioufa +6 more
wiley +1 more source
Revista Colombiana de Antropología, 2009 Este trabajo trata un aspecto de la criminalización de la protesta social: formas criminalizantes en que los funcionarios policiales ven a los manifestantes piqueteros en Argentina. A partir del trabajo de C.
Marcela Perelman
doaj +3 more sources
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background The Completeness of Surgery Index (CoSI) is a novel metric for assessing surgical quality in chronic rhinosinusitis with nasal polyps (CRSwNP). Structured histopathology (SHP) is helpful for characterizing drivers of inflammation. Integrating these two tools to identify patients at higher risk for surgically recalcitrant disease has
Vidit M. Talati +12 more
wiley +1 more source
¿ARGUMENTACIÓN O DEMOSTRACIÓN EN LA DECISIÓN JUDICIAL? UNA MIRADA EN EL ESTADO CONSTITUCIONAL
Revista de Derecho, 2009 El texto plantea el problema en torno a la decisión judicial correcta teniendo en cuenta dos líneas de discusión: primero, la diferenciación en torno a argumentar y demostrar, y segundo, el papel del juez con miras a lograr dicha corrección en el Estado ...
Javier Orlando Aguirre Román +2 more
doaj
Prediction of First and Recurrent Falls in Parkinson's Disease
Annals of Neurology, EarlyView.Objective To develop and externally validate prediction models for next‐year falls in Parkinson's disease (PD), and to evaluate the incremental value of imaging and fluid biomarkers. Methods We developed models in Parkinson's Progression Markers Initiative (PPMI) to predict next‐year falls with external validation in University of Pennsylvania (UPenn ...
Joaquin A. Vizcarra +13 more
wiley +1 more source
Epistemología e Historia de la Ciencia, 2019 Traducción de "L'antinomie de M.
Carlos Alejandro Oller, Chaïm Perelman
doaj +2 more sources
Las subjetividades en vidas de cartón : el cirujeo en la Ciudad de Buenos Aires [PDF]
, 2004 Resumen temporalmente no disponible. La presente obra no cuenta con resumen provisto por el autor.Fil: Perelman, Mariano Daniel. Universidad de Buenos Aires.
Perelman, Mariano Daniel
core +2 more sources
Arthritis &Rheumatology, EarlyView.Objective We employed global genetic deletion of CD14 and intra‐articular CD14 blockade across multiple murine osteoarthritis (OA) models that vary in severity of pathology and rate of progression to test the hypothesis that CD14 inhibition attenuates synovial inflammation and associated pain during disease progression.
Kevin G. Burt +18 more
wiley +1 more source