Results 41 to 50 of about 913,389 (306)

Exploring the Immune-regulating Mechanisms of Ginseng Sea Buckthorn Complex Based on Network Pharmacology

open access: yesShipin gongye ke-ji
This study aimed to investigate the immune-regulating mechanism of the ginseng sea buckthorn complex (GSC) using network pharmacology, molecular docking, cellular experiments, and animal experiments.
Hailin HUANG   +7 more
doaj   +1 more source

Perfective Marking in the Breton Tense-Aspect System

open access: yesLanguages, 2022
The tense-aspect system of Breton, a continental Celtic language, is largely under-described. This paper has two main goals. First, it gives an overview of the numerous verbal morphosyntactic constructions of Breton, with the aim of evaluating how they ...
Éric Corre
doaj   +1 more source

Perfect matchings and perfect squares

open access: yesJournal of Combinatorial Theory, Series A, 1994
The author investigates (perfect) matchings of a large class of graphs with 4-fold rotational symmetry. It is proved by mostly combinatorial arguments that the number of such matchings is always a square or double a square. This result has an interesting application to tilings by dominoes.
openaire   +4 more sources

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Anti-photoaging effects of a topical lotion mediated by coordinated modulation of glutathione metabolism, TGF-β/Smad, and MAPK pathways for extracellular matrix homeostasis

open access: yesJournal of Dermatologic Science and Cosmetic Technology
Background: Skin aging results from intrinsic chronological factors and harmful environmental influences, notably photoaging characterized by UV-induced oxidative stress, which disrupts extracellular matrix (ECM) homeostasis and compromises antioxidant ...
Houcheng Cheng   +8 more
doaj   +1 more source

Modelling morphosyntactic variation in World Englishes from a register perspective

open access: yesMiscelánea: A Journal of English and American Studies, 2017
This paper addresses Miller’s (2000) and Brown and Miller’s (2017) hypothesis that the adverbs just, (n)ever and yet are becoming markers of perfect meaning in spoken English, and this at the expense of weakening semantically and reducing the use of the
Elena Seoane
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Perfect variations in Romance

open access: yesIsogloss, 2022
The morpho-syntactic configuration auxiliary (have or be) + past participle known as the have-perfect functions as a tense-aspect category in many Western European languages.
Henriette de Swart   +3 more
doaj   +1 more source

Perfecting the Nearly Perfect [PDF]

open access: yesPure and Applied Mathematics Quarterly, 2008
We introduce a natural variant of the notion of nearly perfect complex. We show that this variant gives rise to canonical perfect complexes and prove several useful properties of this construction (including additivity of the associated Euler characteristics oil suitable exact triangles).
openaire   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

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