Results 51 to 60 of about 84,386 (305)
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
On the Asymptotic Behavior of Static Perfect Fluids [PDF]
Annales Henri Poincaré, 2019 Static spherically symmetric solutions to the Einstein-Euler equations with prescribed central densities are known to exist, be unique and smooth for reasonable equations of state. Some criteria are also available to decide whether solutions have finite extent (stars with a vacuum exterior) or infinite extent.
Andersson, L., Burtscher, A.
openaire +6 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay +13 more
wiley +1 more source
Ricci-Bourguignon Solitons With Certain Applications to Relativity
Journal of MathematicsThis article concerns with the investigation of Ricci-Bourguignon solitons and gradient Ricci-Bourguignon solitons in perfect fluid space-times and generalised Robertson–Walker space-times.
Krishnendu De +3 more
doaj +1 more source
LP-Kenmotsu Manifolds Admitting Bach Almost Solitons
Universal Journal of Mathematics and ApplicationsFor a Lorentzian para-Kenmotsu manifold of dimension $m$ (briefly, ${(LPK)_{m}}$) admitting Bach almost soliton $(g,\zeta,\lambda)$, we explored the characteristics of the norm of Ricci operator. Besides, we gave the necessary condition for ${(LPK)_{m}}
Mohd Bilal +4 more
doaj +1 more source
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
Static Spherically Symmetric Perfect Fluid Solutions in Teleparallel F(T) Gravity
AxiomsIn this paper, we investigate static spherically symmetric teleparallel F(T) gravity containing a perfect isotropic fluid. We first write the field equations and proceed to find new teleparallel F(T) solutions for perfect isotropic and linear fluids.
Alexandre Landry
doaj +1 more source
A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions
Advanced Engineering Materials, EarlyView.This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice +2 more
wiley +1 more source