Results 61 to 70 of about 1,229 (303)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

A perfectness concept for multicriteria games [PDF]

open access: yes, 1995
This paper considers a refinement of equilibria for multicriteria games based on the perfectness concept of Selten (1975). Existence of perfect equilibrium points is shown and several characterizations are provided.
Borm, P.E.M.   +3 more
core  

ρ-Algorithm: A SICN-Oriented Process Mining Framework

open access: yesIEEE Access, 2021
This paper devises an algorithmic process mining framework characterized by the mathematical process model of structured information control nets (SICN) and the concept of mass-driven $\rho $ -function as a decision-making criterion of structural ...
Kyoung-Sook Kim   +2 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Metric ultraproducts of groups -- simplicity, perfectness and torsion [PDF]

open access: yes
We characterise the simplicity of metric ultraproducts of a family of metric groups. We also present several new examples of simple groups, such as metric ultraproducts of finite and infinite symmetric groups, linear groups, and interval exchange ...
Majcher, Krzysztof   +2 more
core   +2 more sources

Kernels and perfectness in arc-local tournament digraphs [PDF]

open access: yes, 2006
In this paper we give a characterization of kernel-perfect (and of critical kernel-imperfect) arc-local tournament digraphs. As a consequence, we prove that arc-local tournament digraphs satisfy a strenghtened form of the following interesting conjecture
Galeana-Sánchez, Hortensia
core   +1 more source

MENEMUKAN MAKNA AURAT DALAM TAFSIR AL-QUR’AN KLASIK DAN KONTEMPORER

open access: yesUlumuna, 2006
Elucidating meaning of a term which later develops to be a concept need a comprehensive understanding and depth knowledge of the term. Genital (awrât, aurat) which arises to be a debatable concept needs reconsideration in its meaning which recently ...
Emawati Emawati
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

Perfectness is an Elusive Graph Property [PDF]

open access: yes, 2002
A graph property is called elusive (or evasive) if every algorithm for testing this property has to read in the worst case $n\choose 2$ entries of the adjacency matrix of the given graph.
Wagler, Annegret, Hougardy, Stefan
core  

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