Results 1 to 10 of about 36,449 (185)

Developmental exposure to perfluorooctane sulfonate(PFOS) impairs the endometrial receptivity [PDF]

Scientific Reports
Abstract Perfluorooctanoic sulfonate (PFOS) is difficult to degrade and tends to accumulate in the body, which causes widespread concern. The expression of genes related to endometrial receptivity and the differentiation of human endometrial stromal cells (hESCs) were assessed in this study concerning PFOS.
Rui Ren, Xinyue Zhou, Tianyu Jia, Bin Wang, Ahui Liu, Min Gao, Ji Song, Liyan Wang, Yuanxue Jing, Liulin Yu, Haofei Shen, Xuehong Zhang   +11 more
core   +5 more sources

Sediment–water distribution of perfluorooctane sulfonate (PFOS) in Yangtze River Estuary [PDF]

Environmental Pollution, 2010
Analysis of Perfluorooctane sulfonate (PFOS) distribution in water and sediment in Yangtze River Estuary showed that the estuary was a sink for PFOS. Salinity was an important parameter in controlling the sediment-water interactions and the fate or transport of PFOS in the aquatic environment.
Gang, Pan, Chun, You
core   +5 more sources

Nephrotoxicity of perfluorooctane sulfonate (PFOS)—effect on transcription and epigenetic factors [PDF]

Environmental Epigenetics, 2022
AbstractPerfluorooctane sulfonate (PFOS) is a widespread persistent environmental pollutant implicated in nephrotoxicity with altered metabolism, carcinogenesis, and fibrosis potential. We studied the underlying epigenetic mechanism involving transcription factors of PFOS-induced kidney injury.
Yi Wen, Faizan Rashid, Zeeshan Fazal, Ratnakar Singh, Michael J Spinella, Joseph Irudayaraj   +5 more
openaire   +3 more sources

Adverse Effects of Perfluorooctane Sulfonate on the Liver and Relevant Mechanisms

Toxics, 2022
Perfluorooctane sulfonate (PFOS) is a persistent, widely present organic pollutant. PFOS can enter the human body through drinking water, ingestion of food, contact with utensils containing PFOS, and occupational exposure to PFOS, and can have adverse ...
Shuqi Yan, Liu, Dongge, Cui, Jiajing, Jiajing Cui, Ren, Shuping, Pingwei Wang, Yan, Shuqi, Dongge Liu, Shuping Ren, Wang, Pingwei, Liang, Yujun, Yujun Liang   +11 more
core   +2 more sources

Estimating safe doses of perfluorooctane sulfonate (PFOS): an international collaboration [PDF]

Archives of Toxicology
Many government agencies and expert groups have estimated a safe dose (aka a "reference dose," [RfD]) for perfluorooctane sulfonate (PFOS). Notably, these agencies have derived safe doses that vary over at least 600-fold range. The range is larger still if one includes the U.S.
Michael L. Dourson, Laura C. Green, Edmund A. C. Crouch, Harvey J. Clewell, Thomas Colnot, Tony Cox, Wolfgang Dekant, Linda D. Dell, James A. Deyo, Bernard K. Gadagbui, Helmut Greim, Mahesh Rachamalla Gupta, Tamara House-Knight, Ashish Jachak, Vijayavel Kannappan, Travis R. Kline, Therese Manning, Ravi Naidu, Paul Nathanail, Chijioke Onyema, Frank Pagone, Andrew Pawlisz, Tiago Severo Peixe, Katie Richardson, Anurag Sharma, James S. Smith, Nitin Verma, Andrea Wojtyniak, Jackie Wright   +28 more
openaire   +5 more sources

Perfluorooctane Sulfonate (PFOS) Produces Dopaminergic Neuropathology in Caenorhabditis elegans [PDF]

Toxicological Sciences, 2019
AbstractPerfluorooctane sulfonate (PFOS) has been widely utilized in numerous industries. Due to long environmental and biological half-lives, PFOS is a major public health concern. Although the literature suggests that PFOS may induce neurotoxicity, neurotoxic mechanisms, and neuropathology are poorly understood.
Shreesh Raj, Sammi, Rachel M, Foguth, Claudia Sofía, Nieves, Chloe, De Perre, Peter, Wipf, Cynthia T, McMurray, Linda S, Lee, Jason R, Cannon   +7 more
openaire   +4 more sources

Perfluorooctane Sulfonate (PFOS) and Perfluorohexane Sulfonate (PFHxS) Alters Protein Phosphorylation, Increase ROS Levels and DNA Fragmentation during In Vitro Capacitation of Boar Spermatozoa [PDF]

Animals, 2020
Perfluorooctane sulfonate (PFOS) and perfluorohexane sulfonate (PFHxS) are toxic and bioaccumulative, included in the Stockholm Convention’s list as persistent organic pollutants.
Iván Oseguera-López, Serafín Pérez-Cerezales, Paola Berenice Ortiz-Sánchez, Oscar Mondragon-Payne, Raúl Sánchez-Sánchez, Irma Jiménez-Morales, Reyna Fierro, Humberto González-Márquez   +7 more
doaj   +2 more sources

Thyroid disruption by perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA)

Journal of Endocrinological Investigation, 2016
Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) are two fluorinated compounds widely used in industry because of their useful chemical characteristics. They were identified as endocrine disruptors due to their ability to interfere with thyroid function.
Coperchini, F, Awwad, O, Rotondi, M, SANTINI, FERRUCCIO, Imbriani, M, Chiovato, L.   +5 more
openaire   +5 more sources

Probabilistic Human Health Risk Assessment of Perfluorooctane Sulfonate (PFOS) by Integrating in Vitro, in Vivo Toxicity, and Human Epidemiological Studies Using a Bayesian-Based Dose-Response Assessment Coupled With Physiologically Based Pharmacokinetic (PBPK) Modeling Approach

Environment International, 2020
Background: Environmental exposure to perfluorooctane sulfonate (PFOS) is associated with various adverse outcomes in humans. However, risk assessment for PFOS with the traditional risk estimation method is faced with multiple challenges because there ...
Zhoumeng Lin, Wei-Chun Chou
exaly   +3 more sources

Partitioning of perfluorooctanoate (PFOA), perfluorooctane sulfonate (PFOS) and perfluorooctane sulfonamide (PFOSA) between water and sediment

Chemosphere, 2011
Laboratory partitioning experiments were conducted to elucidate the sorption behaviour and partitioning of perfluoroalkyl compounds (PFCs). Three different sediment types were used and separately spiked with perfluorooctanoate (PFOA), perfluorooctane sulfonate (PFOS) and perfluorooctane sulfonamide (PFOSA) at low environmentally realistic ...
Lutz, Ahrens, Leo W Y, Yeung, Sachi, Taniyasu, Paul K S, Lam, Nobuyoshi, Yamashita   +4 more
openaire   +3 more sources