Results 141 to 150 of about 400,764 (338)
Association of peptic ulcer perforation with ramadan related lifestyle modifications.
, 2023 Attiya Nasir Siddique +5 more
openalex +2 more sources
Advanced Science, EarlyView.This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai +12 more
wiley +1 more source
Iatrogenic orifice transluminal endoscopic surgery (IOTES): managing uterine perforations at operative hysteroscopy [PDF]
, 2009 Alexander W. Huber +5 more
openalex +1 more source
Advanced Science, EarlyView.CDGSH iron sulfur domain 1 (CISD1) mitigates oxidative stress by promoting NADH oxidation and Coenzyme Q (CoQ) reduction. Under chronic stress, elevated CISD1 expression in microglia enhances NAD⁺ production, thereby increasing GAPDH activity and glycolytic flux, while reducing ATP synthesis by inhibiting proton transfer from mitochondrial complexes I ...
Wanting Dong +5 more
wiley +1 more source
Advanced Science, EarlyView.The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang +15 more
wiley +1 more source
Advanced Science, EarlyView.Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu +14 more
wiley +1 more source
Ultra Sound Evaluation of Asymptomatic Gall Bladder Perforation
Online Journal of Health & Allied Sciences, 2016 Gall bladder perforation is a rare, fatal and life threatening complication of acute cholecystitis. A definitive diagnosis is uncommon before surgery due to which the morbidity and mortality associated with this condition is high.
Kumar P +3 more
doaj
Blade Sharpness and its Effect on the Testing of Body Armours [PDF]
, 2002 Factors such as edge sharpness and tip sharpness have been identified by Horsfall,1 as keyvariables in the testing of stab and slash resistant armours.
Champion, Stephen M. +3 more
core
Jejunal Diverticulosis With Perforation as a Complication of Fabry's Disease
, 1984 Lawrence S. Friedman +5 more
openalex +1 more source
Advanced Science, EarlyView.Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He +8 more
wiley +1 more source