Results 101 to 110 of about 483,838 (251)

Postmastectomy intensity modulation radiated therapy of chest wall and regional nodes: Retrospective analysis of the performance and complications up for 5 years. [PDF]

Medicine (Baltimore), 2017
Wang Q, Jie W, Liang Z, Wu H, Cheng J.
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

A Novel ex vivo Snare Tip Soft Coagulation Model for Deliberate Self-Practice and Assessing Endoscopic Tip-Control Competency: The HAM-2 Study

Endoscopy International Open
Tamas Tornai, Maria Eva Argenziano, Michele Montori, Pieter Jan Poortmans, Andrea Sorge, Sander Smeets, Lynn Debels, Lobke Desomer, David J. Tate   +8 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Subjective health status, life performance and complications in chronic hypoparathyroidism - a German multicenter survey. [PDF]

Front Endocrinol (Lausanne)
Fuss CT, Engbers S, Reisch N, Hannemann A, Völzke H, Grabe HJ, Nauck M, Droste M, Willenberg HS, Rayes N, Fassnacht M, Quinkler M, Hahner S.   +12 more
europepmc   +1 more source

Efficiency of Investor Owned Firms and Cooperatives Revisited [PDF]

Providing a performance measure of any firm is a crucial issue, not only for the stakeholders of the firm, but also for policy makers, labor unions, and economists.
Soboh, Rafat, van Dijk, Gert, Oude Lansink, Alfons G.J.M.   +2 more
core  

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Effect of training on navigated frameless and frame-based stereotactic brain biopsies: a retrospective comparison of staff neurosurgeon and trainee perioperative performance and complications. [PDF]

Acta Neurochir (Wien)
Joswig H, Nestle SH, Funk JM, Sultanova S, Doenitz C, Seyfried T, Augustin J, Grassmann F, Träger U, Blecha S.   +9 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source