Results 61 to 70 of about 871,539 (301)

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

Audit of the diagnosis and management of adult obesity in a Maltese general practice [PDF]

open access: yes, 2012
Obesity is an escalating health problem all over the world. Unfortunately, Malta lies on the upper end of the spectrum of mean population BMI (body-mass index).
Bonnici, Jason   +2 more
core  

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

open access: yesFEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo   +4 more
wiley   +1 more source

A stag beetle knife can achieve stabler and safer endoscopic submucosal dissection in the esophagus

open access: yesEndoscopy International Open, 2023
Kohei Funasaka   +11 more
doaj   +1 more source

Performance Characteristics of a Clinical Decision Support Tool for Disease Complications in Crohn’s Disease [PDF]

open access: gold, 2021
Corey A. Siegel   +11 more
openalex   +1 more source

Three-flavor analysis of long-baseline experiments

open access: yes, 2004
We compare the analysis of existing and future neutrino oscillation long-baseline experiments, where we point out that the analysis of future experiments actually implies a 12-dimensional parameter space.
Barger   +16 more
core   +2 more sources

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

open access: yesFEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang   +6 more
wiley   +1 more source

Liver resections: complications and survival outcome [PDF]

open access: yes, 2007
none1noToday, liver resection represents one of the most effective therapies in the treatment of defined liver diseases, particularly for hepatocellular carcinomas, liver metastases and tumors originating from the bile ducts.
Grazi, Gian Luca
core   +1 more source

Causing a Ruckus: Complicity and Performance in Stories of Port Moody

open access: yesPublic History Review, 2018
This article is about the suicide of the chief of police of a small Canadian town, which - according to some - did not actually happen. While employed as a researcher and writer with a museum in Port Moody, British Columbia, the author heard this story as one of many told by the ‘old-timers’ who assisted with the writing of a history book.
openaire   +4 more sources

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