Results 91 to 100 of about 498,761 (251)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

2. Pinning information Quick reference data Symbol Parameter Conditions Min Typ Max Unit

open access: yes, 2010
Standard level gate drive N-channel enhancement mode Field-Effect Transistor (FET) in a plastic package using advanced TrenchMOS technology. This product has been designed and qualified to the appropriate AEC standard for use in high performance ...
General Description
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Standard VHDL 1076.1.1 Packages for Multiple Energy Domain Support

open access: yes, 2003
This paper describes the set of packages providing a standard for the declaration of the most frequently used constants and types required for multiple energy domain modeling.
Mantooth, Alan   +2 more
core   +1 more source

Development of a standard series for pump-jet propulsors and data-driven regression for performance prediction

open access: yesInternational Journal of Naval Architecture and Ocean Engineering
Pump-jet propulsors are widely used in marine applications because of their advantages in propulsive efficiency, cavitation performance, and low noise performance.
Jinghan Su   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

LRD2: Low Resource Device Description for Energy Efficient Device Discovery [PDF]

open access: yes, 2011
International audienceThe success of the large scale deployment of sensor actuator devices lies in their plug\&play capabilities: they should be automatically discovered and ready to be used when they join to an environment.
Suarez Coloma, Juan Pablo   +1 more
core   +1 more source

Prediction of Backwater Profiles due to Bridges in a Compound Channel Using CFD

open access: yesAdvances in Mechanical Engineering, 2014
With the advancements in computing power, computational fluid dynamics (CFD) analysis has emerged as a powerful hydraulics design tool. This study aims to assess the performance of CFD via commercially available software (FLOW-3D) in the prediction of ...
Selahattin Kocaman
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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