Results 71 to 80 of about 452,974 (236)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Anomaly Detection-Based UE-Centric Inter-Cell Interference Suppression

IEEE Open Journal of the Communications Society
The increasing spectral reuse can cause significant performance degradation due to interference from neighboring cells. In such scenarios, developing effective interference suppression schemes is necessary to improve overall system performance. To tackle
Kwonyeol Park, Hyuckjin Choi, Beomsoo Ko, Minje Kim, Gyoseung Lee, Daecheol Kwon, Hyunjae Park, Byungseung Kim, Min-Ho Shin, Junil Choi   +9 more
doaj   +1 more source

CROSSOVER OPERATORS IN GENETIC ALGORITHMS: A REVIEW [PDF]

ICTACT Journal on Soft Computing, 2015
The performance of Genetic Algorithm (GA) depends on various operators. Crossover operator is one of them. Crossover operators are mainly classified as application dependent crossover operators and application independent crossover operators.
A.J. Umbarkar, P.D. Sheth
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

<b>A proposed vision for developing the teaching performance of teachers of Arabic to non-native speakers considering quality standards. (Descriptive study)</b><b></b>

SCHOLAR
تهدف هذه الدراسة إلى بناء إطار تربوي تحليلي لتطوير الأداء التدريسي لمعلمي اللغة العربية للناطقين بغيرها في ضوء معايير الجودة التعليمية، انطلاقًا من تحليل واقع الممارسات التدريسية الحالية وتحديد المعايير المهنية اللازمة للارتقاء بكفاءة المعلم. وتعتمد الدراسة المنهج الوصفي التحليلي للكشف عن مستوى الأداء التدريسي في مجالات التخطيط والتنفيذ والتقويم ...
openaire   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Performance evaluation of M-ary algorithm using reprogrammable hardware

Dyna, 2017
Several ways to perform data encryption have been found, and one of the functions involved in standard algorithms such as RSA is the modular exponentiation.
Sergio Andrés Arenas-Hoyos, Álvaro Bernal-Noreña   +1 more
doaj   +1 more source