Results 61 to 70 of about 452,974 (236)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
INTERNATIONAL RATING AGENCIES APPROACHES TO THE EVALUATION OF INSURANCE COMPANIES
Фінансово-кредитна діяльність: проблеми теорії та практики, 2017 Growing need for an independent evaluation of the performance results of insurance companies is due to the need to meet the needs of stakeholders to reliable information about the evaluation results of insurers.
S. A. Achkasova +2 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Biología Acuática, 2019 The description of fish population demographic can be carried out with the estimate of key parameters: asymptotic length and weight (L∞ and W∞ ), growth constant (K), initial number of each cohort at times zero (N0) and mortality coefficient (Z).
Lauce Rubén Freyre +3 more
doaj
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
APLIKASI SISTEM PENGUKURAN PRODUKTIVITAS KAITANNYA DENGAN PENGUPAHAN
Jurnal Teknik Industri, 2006 In every profit or nonprofit oriented organization, human resources are the key factor in achieving the efficiency and effectiveness of the organization. In this paper, we design the technique for measuring the individual productivity in the working area.
Pribadiyono Pribadiyono
doaj
ANALISIS DAYA SAING EKONOMI ANTAR DAERAH DI PROVINSI SUMATERA SELATAN
Jurnal Ekonomi Pembangunan, 2009 This research is aimed to know a description of economic competitiveness in The Province of South Sumatra and to what extend the correlation between economic performance, local finance, and HDI to economic competitiveness. Data used is pooled data (2001-
Sukanto Sukanto
doaj +1 more source