Results 41 to 50 of about 452,974 (236)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Factors Influencing the Performance of Standard Precautions for Preventing Infections among Nurses in Long-Term Care Hospitals: A Cross-Sectional Descriptive Study

Journal of Korean Academy of Fundamentals of Nursing
Purpose: This study aimed to determine the influence of awareness of standard precautions, protective environment on exposure to infection, infection control organizational culture, and moral sensitivity on long-term care hospital nurses’ performance of standard precautions.Methods: A cross-sectional descriptive design was used. This study included 240
Gi Ran Lee, Doo Ree Kim, Sung Ae Choi
openaire   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Krisis as the Scene of Non-Decisional Judgement: A Performance Fiction for the Generic Human

Performance Philosophy, 2018
François Laruelle’s non-standard aesthetics proposes a framework for ‘conjugating’ philosophy with the arts to articulate new models of thought (2012a).
Hannah Lammin
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The use of tools to support oral lesion description in oral medicine referrals

Brazilian Oral Research, 2017
: Poor description of oral lesions jeopardize the prioritization of appointments in Oral Medicine. The present study investigated whether the use of support tools changes the quality of descriptions focusing on health care prioritization.
Caroline Zimmermann, Maria Inês Meurer, Josimari Telino de Lacerda, Ana Lúcia Schaefer Ferreira de Mello, Liliane Janete Grando   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Frame-Based Multiple-Description Video Coding with Extended Orthogonal Filter Banks

EURASIP Journal on Advances in Signal Processing, 2006
We propose a frame-based multiple-description video coder. The analysis filter bank is the extension of an orthogonal filter bank which computes the spatial polyphase components of the original video frames.
Vitali A, Bernardini R, Durigon M, Rinaldo R, Zontone P   +4 more
doaj   +1 more source