Results 91 to 100 of about 3,037,170 (287)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Produção animal e o meio ambiente: uma comparação entre potencial de emissão de metano dos dejetos e a quantidade de alimento produzido Animal production and environment: a comparison between potential of methane emission from waste and quantity of produced food

open access: yesEngenharia Agrícola, 2011
O objetivo do trabalho foi efetuar a comparação das principais espécies de interesse agropecuário, em relação à eficiência de conversão das dietas em produtos de origem animal (carne ou ovo), produção de resíduo e potencial de emissão de metano, a partir
Marco A. P. Orrico Júnior   +2 more
doaj   +1 more source

Revisiting the Three Peculiarities of Production in Construction [PDF]

open access: yes
Compared to many other industries, construction is a specific type of project industry with certain pe- culiarities influencing the characteristics of constructed products, ways of production, and the indus- try itself.
Koskela, Lauri, Vrijhoef, Ruben
core  

Implementation of technology and production strategy practices: relationship levels in different industries [PDF]

open access: yes, 2015
Many industries face open, global markets with requirements for rapid response and low costs. Given the major role that technology plays in business competitiveness, proper technology management (T) in combination with a good production strategy (S), is ...
Garrido-Vega, Pedro   +3 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Les Fondamentaux de la performance industrielle

open access: yesRevue Marocaine de Recherche en Management et Marketing, 2012
Si l’organisation et la gestion des flux physiques de production apparaissent bien comme des déterminants majeurs de la performance d’une entreprise industrielle, il reste en revanche difficile, notamment en raison de la grande complexité des systèmes ...
TETOUANI Samir, Aziz SOULHI
doaj  

UNE VALIDATION DES TEMPS STANDARDS D'OPERATION DANS LE SECTEUR DES SERVICES [PDF]

open access: yes
Cet article décrit, en recourrant aux approches DEA et aux frontières de production stochastisques, la mise en place d'un outil de benchmaking interne dans le secteur des services.
Gervais Thenet
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Méthodologie d’aide à la conception et à l’évaluation de systèmes de production multiperformants : application à l’élevage de bovins laitiers et à la production de poulets de chair

open access: yesINRAE Productions Animales, 2015
Suite à un appel d’offre du Commissariat Général à la Stratégie et à la Prospective du gouvernement français, l’INRA a analysé les possibilités d’évolution des pratiques et des systèmes agricoles français vers des systèmes de production plus durables ...
B. COUDURIER   +6 more
doaj   +1 more source

Spectra of identified hadrons with the ALICE detector in pp and Pb-Pb collisions at the LHC

open access: yes, 2012
The measurement of identified charged-hadron production at mid-rapidity ($|y| < 0.5$) performed with the ALICE experiment at the LHC is presented for pp collisions at $\sqrt{s}$ = 900 GeV and 7 TeV and for Pb--Pb collisions at $\sqrt{s_{NN}}$ = 2.76 TeV.
Preghenella, Roberto
core  

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