Results 141 to 150 of about 69,653,451 (303)

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Desempenho produtivo de juvenis de tambaqui (Colossoma macropomum Cuvier, 1818) alimentados com rações contendo farinha de crueira de mandioca (Manihot esculenta, Crantz) em substituição ao milho (Zea mays) Performance of juvenile tambaqui (Colossoma macropomum Cuvier, 1818) fed diets containing crueira manioc flour (Manihot esculenta, Crantz) in replacement of corn (Zea mays)

Acta Amazonica, 2013
O objetivo deste estudo foi avaliar o desempenho produtivo de juvenis de tambaqui (Colossoma macropomum), alimentados com níveis crescentes de farinha de crueira de mandioca, Manihot esculenta (0%, 20%, 40%, 60%, 80%, 100%), como substituto do milho (Zea
Geraldo Pereira Pereira Junior, Expedita Maria de Oliveira Pereira, Manoel Pereira Filho, Paula de Sousa Barbosa, Eduardo Shimoda, Lian Valente Brandão   +5 more
doaj  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Performances de reproduction et de production laitière des vaches Pie-Noires au Maroc

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1986
L'étude a porté sur 1827 résultats du contrôle laitier effectué sur 807 vaches Frisonne-Holstein élevées dans 24 étables localisées dans 4 régions agricoles. La moyenne de l'âge au premier vêlage est de 29,5 mois, l'intervalle vêlage-fécondation est de 139,4 jours et l'intervalle entre deux vêlages est de 411,2 jours.
I. Boujenane, Maty Ba
openaire   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Conversão de resíduos gordurosos de fritura com a produção de biodiesel por rota catalítica heterogênea [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Ambiental, Florianópolis, 2010Convencionalmente a produção industrial de biodiesel emprega o processo de transesterificação de óleos ...
Souza, Maria Aparecida de
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Comportamiento productivo de vacas lecheras Mambí de Cuba en una asociación de gramíneas y Leucaena leucocephala cv. Cunningham Productive performance of Cuban Mambí dairy cows in an association of grasses and Leucaena leucocephala cv. Cunningham

Pastos y Forrajes, 2008
Se evaluó el comportamiento de los indicadores productivos de vacas Mambí (¾ Holstein x ¼ Cebú) de Cuba en una asociación de gramíneas mejoradas y Leucaena leucocephala cv. Cunningham, en una vaquería de la Empresa Genética de Matanzas.
Tania Sánchez, L Lamela, O López, M Benítez   +3 more
doaj  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source