Results 121 to 130 of about 18,296,819 (294)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Il ruolo del design nella progettazione alberghiera

, 2014
l'autore è stato invitato a stendere un contributo sul ruolo del design nell'ambito della progettazione alberghiera, evidenziando le varie declinazioni della disciplina- design strategico, design dei servizi, design della comunicazione, interior design,
SCULLICA, FRANCESCO, dipartimento di design   +1 more
core  

Heat and mass transfer in the semi-underground double-storey squat silo: a numerical analysis during static grain storage

Case Studies in Thermal Engineering
The semi-underground double-storey squat silo (SDSS) is innovative storage structure. The underground section of SDSS uses shallow geologic energy for low-temperature storage, indicating its potential suitability for long-term grain storage under ...
Libing Jin, Tian Wu, Doudou Zhu, Yun Zhao, Zhenqing Wang   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Performance as a Design Driver in Robotic Timber Construction

, 2009
In the research project presented in this paper we investigate the architectonic and constructive potential of additive digital fabrication in timber construction through robotic processes as well as the relation of functional requirements of an exterior
S. Oesterle
core  

Analysis of Train-Induced Vibration Transmission and Distribution Characteristics in Double-Layer Metro Depot

Buildings
When urban subway trains run in the depot, they can cause vibration and noise, which affects the safety and reliability of the structure under the track, and these transmits to the over-track buildings and often trouble passengers and staff.
Xinwei Luo, Xuan Jiang, Qingsong Feng, Wenlin Hu, Qinming Tu, Yanming Chen   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Fabrication of Invar/MnCu bimetallic structure by laser powder bed fusion: Microstructure, mechanical, thermal expansion and damping properties

Journal of Materials Research and Technology
Metallic bimetal structures that combine thermal stability and vibration damping are crucial for advanced structural–functional applications. Conventional joining methods restrict geometric complexity and can damage the interface. Laser powder bed fusion
Yongsheng Deng, Yijie Peng, Mingji Dang, Yue Du, Xiyang Lv, Long Geng, Zhongxuan Liu, Wei Fan, Haiou Yang, Xin Lin, Hua Tan   +10 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Pile Design Practice and Seismic Performance Concerns in Taiwan

, 2011
This paper introduces the current pile design practice in Taiwan with seismic performance concerns in demand. The current geotechnical code was published in 2001 based on traditional design methods.
Chang, D.W.; Yang, T.Y.; Cheng, S.H.; Chin, C.T.; Su, T.C.; Huang, F.K.
core   +1 more source