Results 221 to 230 of about 9,772,737 (279)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Oral Antidiabetic Agents: From Routine Quality Control to Bioanalysis. [PDF]

open access: yesMolecules
Toma AM   +5 more
europepmc   +1 more source

Erythropoiesis-Targeted Doping in Sports: From Improved Oxygen Transport to Cardiovascular Risk. [PDF]

open access: yesPathophysiology
Chlebowska G   +3 more
europepmc   +1 more source

Editorial: using substances to enhance performance

open access: yes, 2018
Wolff, Wanja   +1 more
openaire   +1 more source

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