Results 231 to 240 of about 6,044,315 (278)

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Performance evaluation of rapid diagnostic tests for Chagas disease in Jutiapa, Guatemala. [PDF]

open access: yesRev Soc Bras Med Trop
Lange K   +8 more
europepmc   +1 more source

Review of simplified testing method for performance evaluation to assist in the selection of chemical protective gloves. [PDF]

open access: yesEnviron Occup Health Pract
Iwasawa S   +10 more
europepmc   +1 more source

Performance evaluation of ESR dosimeters under proton beam FLASH irradiation conditions. [PDF]

open access: yesJ Radiat Res
Kumagai J   +7 more
europepmc   +1 more source

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