Results 131 to 140 of about 1,111,933 (311)

The importance of relative performance feedback information: Evidence from a natural experiment using high school students [PDF]

open access: yes
We study the effect of providing relative performance feedback information on performance, when individuals are rewarded according to their absolute performance.
Nagore Iriberri, Ghazala Azmat
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Heterosis from crosses among British breeds of beef cattle : straightbred versus crossbred cows

open access: yes, 1985
The second phase of a long-term beef cattle crossbreeding experiment involving the Angus, Hereford and Shorthorn breeds was conducted at the Shenandoah Valley Research Station, Steeles Tavern, Virginia. Records of 604 matings and 567 births from 120 cows
McClure, William H.   +2 more
core  

Evaluation method of snow melting performance of composite anti-icing and snow melting asphalt mixture

open access: yesResults in Engineering
In this paper, the road performance and ice and snow melting performance of TH-ME5 phase change material and T-SEN salt release material composite asphalt concrete pavement are studied.
Wei Zhang   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Corn performance tests in Virginia in 1960

open access: yes, 1961
Results of corn testing in Virginia in 1960Research Division ...
Schulkcum, Ed, Genter, C.F.
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Corn performance tests in Virginia in 1962

open access: yes, 1963
Results of corn testing in Virginia in 1962Research Division ...
Shulkcum, Edward, 1904-   +1 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Performance of corn hybrids tested in Virginia, 1951-1956

open access: yes, 1957
Presents results of corn hybrids tested in Virginia from 1951 to 1956Research Division ...
Shulkcum, Edward, 1904-   +1 more
core  

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