Results 111 to 120 of about 3,955,631 (310)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An ode to joy : a season of grief [PDF]

open access: yes, 2010
Beethoven's Ninth in Bailey Hall the other evening, April 20, ending in an instant standing ovation by a clearly enchanted audience, was an unforgettable experience. And, like all such truly extraordinary events that are marked not only by artistic merit,
Deinert, Herbert
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

An Interview About a Husband’s Death [PDF]

open access: yes, 2009
The respondent discusses her husband's death in a car accident.The fifty one audio and nine video files in this collection include: villages’ life stories, circle-dancing songs and performance, local history, folk tales, and interviews from Siyuewu ...
G.yu lha
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Crossing paths: revisiting Schumann in history and performance, March 18-April 12, 2006 [PDF]

open access: yes, 2006
This is the concert program of Crossing Paths: Revisiting Schumann in History and Performance festival running from Saturday, March 18- Wednesday, April 12, 2006 , at the College of Fine Arts, 855 Commonwealth Avenue.
School of Music, Boston University
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Plasticity effects in subsequent simulations of car structures [PDF]

open access: yes, 2003
In order to further reduce the weight of car components while at the same time\ud maintaining performance and safe life it is necessary to enhance the simulation process.
Kose, Kim, Rietman, Bert
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

The Relationships between High School Subjects in terms of School Satisfaction and Academic Performance in Mexican Adolescents [PDF]

open access: yes, 2019
Adolescents’ academic performance and the way it is related to their subjective wellbeing are issues of great interest across educational systems. The purpose of this study was to ascertain how satisfaction with high school subjects can predict school ...
Baena Extremera, Antonio   +2 more
core   +1 more source

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