Results 71 to 80 of about 3,955,631 (310)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Some demonstrations to introduce the art of performance

open access: yesVisualidades, 2016
The article discusses some notions related to performances parting from examples, some well-known to the specialized audience, with the intention to introduce questions around performance art, presenting some celebrated performance work.
Carina Sehn, Paola Zordan
doaj   +1 more source

Mean-Variance Optimization in Markov Decision Processes [PDF]

open access: yes, 2011
We consider finite horizon Markov decision processes under performance measures that involve both the mean and the variance of the cumulative reward. We show that either randomized or history-based policies can improve performance.
Mannor, Shie, Tsitsiklis, John
core   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

An Interview Life Story [PDF]

open access: yes, 2009
The respondent tells of her experiences of decollectivization.The fifty one audio and nine video files in this collection include: villages’ life stories, circle-dancing songs and performance, local history, folk tales, and interviews from Siyuewu ...
G.yu lha
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Villagers Relaxing After Circle Dances [PDF]

open access: yes, 2010
Villagers relax and play together after performing circle dances.The fifty one audio and nine video files in this collection include: villages’ life stories, circle-dancing songs and performance, local history, folk tales, and interviews from Siyuewu ...
G.yu lha
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Should Theatre Disappear Like Soap Bubbles?

open access: yesProceedings from the Document Academy, 2018
I recently read an excerpt from a 2004 interview with Peter Hall where he claims that he was happy for his materials to disappear "like soap bubbles" (Reason, 2006).
Erin Lee
doaj   +1 more source

Entangled Performance Histories

open access: yes, 2022
Entangled Performance Histories is the first book-length study that applies the concept of "entangled histories" as a new paradigm in the field of theater and performance historiography."Entangled histories" denotes the interconnectedness of multiple histories that cannot be addressed within national frameworks.
Erika Fischer-Lichte   +4 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy