Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
A bioeconomic performance index for comparison of an experimental intensive aquaponic system with tilapia and tomato versus aquaculture and hydroponics. [PDF]
De León-Ramírez JJ +4 more
europepmc +1 more source
Estimation of process performance index for the two-parameter exponential distribution with measurement error. [PDF]
Li Y, Chiang JY, Bai Y, Chai KC.
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Prospective Evaluation of Automated Right and Left Ventricular Myocardial Performance Index in Late-Onset Fetal Growth Restriction. [PDF]
Reyhan Toptas G +7 more
europepmc +1 more source
Modified Myocardial Performance Index in Fetal Growth Disturbances as Diagnostic and Prognostic Adjunct. [PDF]
Şimşek A, Köse S.
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Fluid challenge and left ventricular myocardial performance index assessed by transthoracic echocardiography with tissue Doppler imaging in critically ill patients with regular rhythm. [PDF]
Talpoș MT +5 more
europepmc +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Right ventricular myocardial performance index as an early marker of cardiac dysfunction in systemic sclerosis. [PDF]
Kaya E +4 more
europepmc +1 more source

