Results 171 to 180 of about 12,857,409 (300)

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Diagnostic value of the myocardial performance index and doppler parameters in detecting fetal growth restriction in pregnancies complicated by hypertensive disorders. [PDF]

Quant Imaging Med Surg
Peng Y, Feng W, Yue S, He Y, Liao X, Wei Z, Gan L, Zhang J.   +7 more
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Social inequalities in self-rated health in Sweden using the Population Health Performance Index: a cross-sectional study. [PDF]

Eur J Public Health
Inyangetuk RS, San Sebastián M, Fonseca-Rodríguez O.   +2 more
europepmc   +1 more source

Impact of COVID-19 on Sustainability Enablers and Evaluation of Performance Index. [PDF]

Mater Today Proc, 2022
Prajapati D, Agarwal S, Murtaza Q.
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Intrapartum Fetal Compromise in Late-Onset Fetal Growth Restriction Using the Modified Myocardial Performance Index: A Prospective Cohort Study. [PDF]

Medicina (Kaunas)
Kaya Y, Alpay V, Dagdeviren E, Yaman İ.
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Application of the Performance Index for Monitoring Anaerobic Endurance of Competitive Swimmers. [PDF]

J Hum Kinet
Kuliś S, Jabłoński T, Rossi C, Skorulski M, Kossek A, Sienkiewicz-Dianzenza E, Pietraszewski P, Gołaś A, Gajewski J.   +8 more
europepmc   +1 more source

How Automated Techniques Ease Functional Assessment of the Fetal Heart: Applicability of MPI+™ for Direct Quantification of the Modified Myocardial Performance Index. [PDF]

Diagnostics (Basel), 2023
Scharf JL, Dracopoulos C, Gembicki M, Welp A, Weichert J.   +4 more
europepmc   +1 more source