Results 91 to 100 of about 5,794,591 (330)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

The influence of knowledge-hiding behavior on academic performance: empirical evidence from undergraduate students in Vietnam [PDF]

open access: yesKnowledge & Performance Management
This study aims to investigate the impact of knowledge-hiding behavior on individual creativity and academic performance through the mediating role of academic self-efficacy.
Tran Hai Yen   +3 more
doaj   +1 more source

THE STRATEGIC PERFORMANCE MANAGEMENT PROCESS [PDF]

open access: yes
Contemporary trends in global competition, rapid technological developments and increased use of management information systems and the Internet, developments in planning and control and management thinking, and changing demographics are putting ...
Bagu Constantin   +2 more
core  

The Influence of Impression Management in Sustainability Reports on Company’s Performance [PDF]

open access: yes, 2017
This study is aimed to investigate the effect of impression management of the company performance. The impression management was measured by selectivity, distortion, narcissism and the company’s performance was measured by ROA and Tobin’s Q.
HARTO, Puji, RIYANI, Gusti Ayu Komang
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

The Determinants of the Relationship of Corporate Social Performance and Financial Performance: Conceptual Framework [PDF]

open access: yes, 2012
The objective of this paper is to investigate relationship between CSP and CFP using contingency perspective derived from the strategic management domain. The investigation will be done using lens of slack resource and
Fauzi, Hasan
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Integrating knowledge management with smart technologies in public pharmaceutical organizations [PDF]

open access: yesKnowledge & Performance Management
This study investigates the impact of Knowledge Management (KM) practices, enhanced by smart technologies, on organizational performance within public pharmaceutical organizations in Cairo Governorate, Egypt.
Muhanad Mahmoud   +3 more
doaj   +1 more source

The impact of knowledge management processes on organisational performance [PDF]

open access: yes, 2012
Copyright @ 2012 ISEing.In today's increasingly competitive business environment, the use of knowledge to gain a competitive advantage has become a serious concern for all organisations.
Alshawi, SN, Tubigi, MA
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

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