Results 131 to 140 of about 19,525,905 (384)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Biophysical Modelling and Performance Measurement [PDF]
Agricultural production, by its nature, impacts both positively and negatively on the environment. Impacts can be point source or diffuse; however all should be considered in performance measurement.
Graham, Mary
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
FEATURES CONCERNING COMPETITIVE PERFORMANCE MEASUREMENT [PDF]
Innovation and competitiveness are the main vectors of social-economic progress of every country. Starting from this general context and considering the particular context wherein Romania is, which strongly impose the growth of economic competitiveness ...
Cristina Coculescu
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
High-performance liquid chromatography and UV-visible measurements to optimize the storage of volume holograms in hydrogels [PDF]
, 2023 Kheloud Berramdane +9 more
openalex +1 more source
Understanding Process Performance Measurement Systems [PDF]
The purpose of this paper is to analyze the current state of Process Performance Measurement Systems (PPMS) by means of a systematic review of literature. The PPMS literature is reviewed using a systematic approach.
Ljubica Milanović Glavan
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Pursuing Equity in Performance Measurement. [PDF]
Circulation, 2023 Heidenreich P, Sandhu A.
europepmc +1 more source
Performance measurement in blind audio source separation
IEEE Transactions on Audio, Speech, and Language Processing, 2006 E. Vincent, R. Gribonval, C. Févotte
semanticscholar +1 more source