Results 161 to 170 of about 11,995,189 (293)

Present state analysis of business performance measurement systems in large manufacturing companies [Elektronisk resurs]

, 2016
The purpose of this article is to empirically investigate the present state of the performance measurement systems (PMS) at 7 sites of 6 different large Swedish manufacturing companies.
Martin, Kurdve,, Myrelid, Andreas,, Andersson, Carin,, Wiktorsson, Magnus,, Windmark, Christina,, Shabazi, Sasha,, Öberg, Anna Ericson,, Lund University., Landström, Anna,, Winroth, Mats,, Almström, Peter,, Zackrisson, Mats,   +11 more
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Military veterans wellness program: Performance measurement framework. [PDF]

J Mil Veteran Fam Health
Dale AL, Dale A, Burns J, Dale G, Collins P, Ellis J.   +5 more
europepmc   +1 more source

Quality Measurement as a Path to High Quality Care Comment on "Quality and Performance Measurement in Primary Diabetes Care: A Qualitative Study in Urban China". [PDF]

Int J Health Policy Manag, 2023
Matulis Iii JC, McCoy RG.
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Effect of disability, homelessness, and neighborhood marginalization on risk adjustment for hospital performance measurement. [PDF]

Am J Epidemiol
Roberts SB, Colacci M, Shi J, Brown HK, Ashraf M, Stukel T, Razak F, Verma AA.   +7 more
europepmc   +1 more source

Performance Measurement for Opioid Use Disorder Medication Treatment and Care Retention. [PDF]

Am J Psychiatry, 2023
Williams AR, Mauro CM, Feng T, Wilson A, Cruz A, Olfson M, Crystal S, Samples H, Chiodo L.   +8 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The beast and the burden: will pruning performance measurement improve quality? [PDF]

BMJ Qual Saf
Schneider EC.
europepmc   +1 more source

Stakeholders' Perceived Barriers and Successes of Quality Improvement Programs for Patients With Diabetes Comment on "Quality and Performance Measurement in Primary Diabetes Care: A Qualitative Study in Urban China". [PDF]

Int J Health Policy Manag, 2023
Neumann A.
europepmc   +1 more source