Results 171 to 180 of about 4,046,779 (307)

An Empirical Framework for Assessing the Balanced Scorecard Impact on Sustainable Development in Healthcare Performance Measurement. [PDF]

Int J Environ Res Public Health, 2022
Vărzaru AA.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Pragmatics prevail over paradigms in a war of supremacy for physical education

Frontiers in Sports and Active Living
Dean Alan Dudley, Dean Alan Dudley, Dean Alan Dudley   +2 more
doaj   +1 more source

Primary health care performance measurement at the service delivery level in Indonesia: a scoping review. [PDF]

BMC Health Serv Res
Solikha DA, Butler DC, Setiawan E, Korda RJ, Kelly M.   +4 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Outcome metrics in recommended performance measurement tools for emergency department performance evaluation: a systematic review. [PDF]

Scand J Trauma Resusc Emerg Med
Toukola TK, Mertanen RKK, Kaartinen JM, Tuunainen EA, Castrén MK, Torkki PM.   +5 more
europepmc   +1 more source

Quality and Performance Measurement in Primary Diabetes Care: A Qualitative Study in Urban China. [PDF]

Int J Health Policy Manag, 2022
Rasooly A, Pan Y, Tang Z, Jiangjiang H, Ellen ME, Manor O, Hu S, Davidovitch N.   +7 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Performance measurement and evaluation of health practitioner regulation: A scoping review protocol. [PDF]

PLoS One
Chiu P, Leslie K, Jang G, Adams TL, Thiessen N, Kung JY.   +5 more
europepmc   +1 more source

The Performance of Primary Healthcare in China: The Need for a Systematic Design for Improvement Comment on "Quality and Performance Measurement in Primary Diabetes Care: A Qualitative Study in Urban China". [PDF]

Int J Health Policy Manag, 2023
Jian W, Li Q, Zhang L.
europepmc   +1 more source