Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Manufacturing strategies in action: the case of electro-electronic domestic appliances (EDA)
Brazilian Journal of Operations & Production Management, 2010 The companies’ manufacturing strategies are frequently conceived at business strategic levels and put into practice along their value chains. Based on a company’s position, mission, values and vision, strategic planning defines a trajectory, as well as ...
Oswaldo A. Nogara Borges Oswaldo A. Nogara Borges De Menezes +2 more
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Organizational performance of Olympic sport governing bodies: dealing with measurement and priorities [PDF]
, 2010 Mathieu Winand +3 more
openalex +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
High-Performance Image-Based Measurements of Biological Forces and Interactions in a Dual Optical Trap [PDF]
, 2019 Jessica L. Killian +2 more
openalex +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Optical design and performance analysis of a CubeSat-sized limb sounder utilizing a spatial heterodyne spectrometer for the measurement of mesospheric temperature [PDF]
, 2019 Martin Kaufmann +12 more
openalex +1 more source
Turning performance measurement on its head: From the measurement of performance to the performativity of measuring [PDF]
, 2023 Ed Vosselman, Ivo De Loo
openalex +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Evaluation of the Effectiveness of Insurance Branches Using Data Envelopment Analysis (DEA) (Case study: Branches of Insurance Company in the Southern Provinces of Iran) [PDF]
مدیریت بهره وری, 2013 Evaluation of the effectiveness of organizations has always been the concern of researchers. Hence, over the years numerous techniques for doing this have been proposed and used.
Mahmood Dniyali dah hooz, Saede Ketabi
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