Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Assessment of ambulance interventions; proposal of a performance measurement framework for healthcare improvement in EMS response to patient collapse. [PDF]
Idris K+5 more
europepmc +1 more source
Establishing a Foundation for Performance Measurement for Local Public Health Preparedness. [PDF]
Schlegelmilch J+4 more
europepmc +1 more source
THERMAL PERFORMANCE MEASUREMENTS OF A GRAPHITE TUBE COMPACT CRYOGENIC SUPPORT FOR THE SUPERCONDUCTING SUPER COLLIDER [PDF]
J. D. Gonczy+6 more
openalex +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Primary care performance measurement in Brazil (Previne Brasil Program), 2022-2023. [PDF]
de Souza CDF+7 more
europepmc +1 more source
Validity and Test-retest Reliability of the Jumpo App for Jump Performance Measurement. [PDF]
Vieira A+4 more
europepmc +1 more source
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
A transparent and standardized performance measurement platform is needed for on-prescription digital health apps to enable ongoing performance monitoring. [PDF]
Welzel C+4 more
europepmc +1 more source
S-PI: A performance measurement system using an S-curve. [PDF]
Leal JE, Krakovics F, Vieira VDN.
europepmc +1 more source