Results 171 to 180 of about 1,885,562 (317)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

The Dynamic International Optimal Hedge Ratio

Instead of modeling asset price and currency risks separately, this paper derives the international hedge portfolio, hedging asset price and currency risk simultaneously for estimating the dynamic international optimal hedge ratio.
Liu, Xiaochun, Jacobsen, Brian
core  

A Reed-Solomon Coded DS-CDMA System Using Noncoherent M-ary Orthogonal Modulation over Multipath Fading Channels

, 2000
The performance of Reed–Solomon (RS) coded direct-sequence code division multiple-access (DS-CDMA) systems using noncoherent M-ary orthogonal modulation is investigated over multipath Rayleigh fading channels.
Yang, L-L., Hanzo, L., Yen, K.
core  

Packet delivery ratio performance.

This paper is a follow-up to a recent work by the authors on recoverable UAV-based energy-efficient reconfigurable routing (RUBER) scheme for addressing sensor node and route failure issues in smart wireless livestock sensor networks. Time complexity and
Mohammad S. Shahriar (17743287), Yusuf A. Sha’aban (16052906), Abdulazeez F. Salami (17743284), Mohammed A. Alanezi (17743290), Mouaaz Nahas (5050373), Houssem R. E. H. Bouchekara (17743281)   +5 more
core   +1 more source

Exploring the impact of ESG controversies on private hospital performance in China. [PDF]

Medicine (Baltimore)
Yang H, Xu J.
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Kimball's prudence and two-fund separation as determinants of mutual fund performance evaluation [PDF]

We consider investors with mean-variance-skewness preferences who aim at selecting one out of F different funds and combining it optimally with the riskless asset and direct stock holdings.
Gürtler, Marc, Breuer, Wolfgang
core  

Energy dissipation ratio performance.

This paper is a follow-up to a recent work by the authors on recoverable UAV-based energy-efficient reconfigurable routing (RUBER) scheme for addressing sensor node and route failure issues in smart wireless livestock sensor networks. Time complexity and
Mohammad S. Shahriar (17743287), Yusuf A. Sha’aban (16052906), Abdulazeez F. Salami (17743284), Mohammed A. Alanezi (17743290), Mouaaz Nahas (5050373), Houssem R. E. H. Bouchekara (17743281)   +5 more
core   +1 more source

Associations Between Isokinetic Knee Strength at Different Angular Velocities and Explosive Jump Performance in Young Female Athletes: A Pilot Study. [PDF]

J Funct Morphol Kinesiol
Falat Leütterová D, Sučka J.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source