Results 31 to 40 of about 825,159 (286)

Indexed oxygen delivery during pediatric cardiopulmonary bypass is a modifiable risk factor for postoperative acute kidney injury

The Journal of ExtraCorporeal Technology, 2023
Background: Acute kidney injury after pediatric cardiac surgery is a common complication with few established modifiable risk factors. We sought to characterize whether indexed oxygen delivery during cardiopulmonary bypass was associated with ...
Dreher Molly, Min Jungwon, Mavroudis Constantine, Ryba Douglas, Ostapenko Svetlana, Melchior Richard, Rosenthal Tami, Nuri Muhammad, Blinder Joshua   +8 more
doaj   +1 more source

Mild hyperthermia enhances sensitivity of gastric cancer cells to chemotherapy through reactive oxygen species–induced autophagic death

Tumor Biology, 2017
Mild hyperthermia enhances anti-cancer effects of chemotherapy, but the precise biochemical mechanisms involved are not clear. This study was carried out to investigate whether mild hyperthermia sensitizes gastric cancer cells to chemotherapy through ...
Ming-Chen Ba, Hui Long, Shu-Zhong Cui, Yuan-Feng Gong, Zhao-Fei Yan, Shuai Wang, Yin-Bing Wu   +6 more
doaj   +1 more source

Usefulness of a visual aid in achieving optimal positioning for spinal anesthesia: a randomized trial

BMC Anesthesiology, 2018
Background Optimal patient positioning is perceived as an essential factor to increase the success of performing neuraxial blockade. The primary objective of this study was to evaluate the benefit of using a visual image in addition to verbal ...
Usha Gurunathan, Shakeel Meeran Kunju, Karen Elizabeth Hay, Sharyn van Alphen   +3 more
doaj   +1 more source

Regulatory effects of blood constituents on the function and metabolism of the cat brain in perfusion ezperiments. Brain perfusion with artificial blood containing low molecular dextran and amino acids [PDF]

, 1967
As a link in a series of studies on the effects of blood constituents on the brain function by means of brain perfusion, we used four kinds of artificial blood; namely, the blood containing a low molecular dextran, one containing glutamic acid, one ...
Edamatsu, Kazuyasu, Morimitsu, Junsuke, Nakashima, Yoshihiko, Okumura, Nikichi, Otsuki, Saburo, Watanabe, Shosuke   +5 more
core   +1 more source

Novel portable hypothermic machine perfusion preservation device enhances cardiac viability of donated human hearts

Frontiers in Cardiovascular Medicine
IntroductionHeart transplant remains the gold standard treatment for patients with advanced heart failure. However, the list of patients waiting for a heart transplant continues to increase.
Kristina Andrijauskaite, Rafael J. Veraza, Riley P. Lopez, Zach Maxwell, Isabella Cano, Exal E. Cisneros, Israel J. Jessop, Maria Basurto, George Lamberson, Michelle D. Watt, Joseph Nespral, Masahiro Ono, Leonid Bunegin   +12 more
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

A novel strategy for conversion from pediatric V-A ECMO to CPB circuit

The Journal of ExtraCorporeal Technology
This article describes two novel strategies to convert a veno-arterial extracorporeal membrane oxygenator (V-A ECMO) supported pediatric patient circuit to a cardiopulmonary bypass (CPB) circuit.
Lal Amita, Machin David, Lansdowne William   +2 more
doaj   +1 more source

Do continuous forms of intra-operative ultrafiltration enhance recovery after adult cardiac surgery with cardiopulmonary bypass? A protocol for systematic review and meta-analysis of randomized controlled trials

Systematic Reviews, 2021
Background Cardiac surgery with cardiopulmonary bypass (CPB) is associated with a systemic inflammatory syndrome that adversely impacts cardiopulmonary function and can contribute to prolonged postoperative recovery.
Joel Bierer, David Horne, Roger Stanzel, Mark Henderson, Leah Boulos, Jill Hayden   +5 more
doaj   +1 more source

Computer-assisted ex vivo, normothermic small bowel perfusion [PDF]

, 2000
Background: In the present study, a technique for computer-assisted, normothermic, oxygenated, ex vivo, recirculating small bowel perfusion was established as a tool to investigate organ pretreatment protocols and ischemia/reperfusion phenomena.
Eder, M., Hammer, C., Krapp, J., Land, W., Schildberg, Friedrich Wilhelm, Stangl, M. J., Theodorou, D.   +6 more
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source