Results 31 to 40 of about 645,807 (300)

Improved quantification of perfusion in patients with cerebrovascular disease. [PDF]

, 2008
In recent years measurements of cerebral perfusion using bolus-tracking MRI have become common clinical practice in the diagnosis and management of patients with stroke and cerebrovascular disease. An active area of research is the development of methods
Willats, L.
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Is continuous in-line blood gas monitoring reliable during cardiopulmonary bypass when PaO2 and PaCO2 are calculated rather than measured?

The Journal of ExtraCorporeal Technology
Background: The accuracy and precision of continuous in-line blood gas monitoring (CILBGM) are crucial for optimal blood gas management during cardiopulmonary bypass (CPB) and improved patient outcomes.
Lee Min-Ho, Rosenthal Tami
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Adapting and applying student-centered learning in a perfusion clinical rotation

The Journal of ExtraCorporeal Technology
While the process of teaching student perfusionists has been in development since the 1950s, the publication of the processes to improve perfusion clinical education has been largely lacking.
Neal James R., Blau Caitlin, Colby Clint
doaj   +1 more source

Xenogeneic, extracorporeal liver perfusion in primates improves the ratio of branched-chain amino acids to aromatic amino acids (Fischer's ratio) [PDF]

, 1999
In fulminant hepatic failure (FHF), the development of hepatic encephalopathy is associated with grossly abnormal concentrations of plasma amino acids (PAA).
Puhl, G., Neuhaus, P., Schön, M. R., Hammer, C., Matthes, M., Heil, W., Lemmens, H.-P., Padval, D.   +7 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Do continuous forms of intra-operative ultrafiltration enhance recovery after adult cardiac surgery with cardiopulmonary bypass? A protocol for systematic review and meta-analysis of randomized controlled trials

Systematic Reviews, 2021
Background Cardiac surgery with cardiopulmonary bypass (CPB) is associated with a systemic inflammatory syndrome that adversely impacts cardiopulmonary function and can contribute to prolonged postoperative recovery.
Joel Bierer, David Horne, Roger Stanzel, Mark Henderson, Leah Boulos, Jill Hayden   +5 more
doaj   +1 more source

Evaluation of membranes for use in on-line cell separation during mammalian cell perfusion processes [PDF]

, 1994
Büntemeyer H, Bohme C, Lehmann J. Evaluation of membranes for use in on-line cell separation during mammalian cell perfusion processes. Cytotechnology. 1994;15(1-3):243-251.In this study two microporous hollow fibre membranes were evaluated for their use
Lehmann, Jürgen, Bohme, Christoph, Büntemeyer, Heino   +2 more
core   +1 more source

Coronary perfusion pressure is associated with adverse outcomes in advanced heart failure

, 2022
Background Myocardial perfusion is an important determinant of cardiac function. We hypothesized that low coronary perfusion pressure (CPP) would be associated with adverse outcomes in heart failure.
Mwenya Mubanga, Christiana Jeukeng, Mazimba, S, Mwansa, Hunter, Kenneth Bilchick, Hunter Mwansa, Comfort Elumogo, Kwon, Y, Mwansa, V, Jeukeng, Christiana, Elumogo, Comfort, Nishaki Mehta, Baldeo, Cherisse, Elumogo, C, Mehta, Nishaki, Cherisse Baldeo, Jeukeng, C, Christian Selinski, Ibrahim, Sami, Mwansa, H, Sula Mazimba, Sami Ibrahim, Khadijah Breathett, Breathett, K, Mubanga, Mwenya, Ondigi, O, Selinski, Christian, Bilchick, Kenneth, Johnson, AE, Kwon, Younghoon, Younghoon Kwon, Johnson, Amber E, Ondigi, Olivia, Amber E Johnson, Breathett, Khadijah, Victor Mwansa, Mubanga, M,, Mwansa, Victor, Mazimba, Sula, Olivia Ondigi   +39 more
core   +1 more source