Results 111 to 120 of about 263,898 (315)

Microfabricated Anisotropic Myobundles for the Scalable Production of Cardiac Tissue Grafts

Advanced Functional Materials, EarlyView.
Controlling the anisotropy of cardiac tissue remains an outstanding challenge in the field of cardiac tissue engineering. Here, we introduce an approach to generate anisotropic cardiac myobundles using cell‐adhesive, synthetic, electrospun fibers and stem cell‐derived cardiac fibroblasts.
Maggie E. Jewett, Javiera Jilberto, Margaret E. Stanley, David O. Ntim, Siddhi M. Bhirud, Avianna T. Schroeder, Gonzola X. Anyosa Galvez, Jingyi Xia, Samuel J. DePalma, Emmanouil Agrafiotis, Susan S. Xi, Amanda S. Bluem, Courtney M. Lestock, Adam S. Helms, David A. Nordsletten, Brendon M. Baker   +15 more
wiley   +1 more source

Functional imaging of cerebral perfusion

Diagnostic and Interventional Imaging, 2013
The functional imaging of perfusion enables the study of its properties such as the vasoreactivity to circulating gases, the autoregulation and the neurovascular coupling. Downstream from arterial stenosis, this imaging can estimate the vascular reserve and the risk of ischemia in order to adapt the therapeutic strategy.
Krainik, A., Villien, M., Troprès, I., Attyé, A., Lamalle, L., Bouvier, J., Pietras, J., Grand, S., Le Bas, J.-F., Warnking, J.   +9 more
openaire   +2 more sources

Multimodality Imaging of Tumour Pathophysiology and Response to Pharmacological Intervention

, 2015
This thesis describes the need for imaging the tumour pathophysiological microenvironment in order to understand response to treatment. Specifically looking at tumour vascularisation in in vivo murine xenograft models of disease, response to treatment ...
Johnson, SP
core  

Contrast-Enhanced Ultrasound for Myocardial Perfusion Imaging

, 2012
Ultrasound contrast agents are gas-filled microbubbles that enhance visualization of cardiac structures, function and blood flow during contrast-enhanced ultrasound (CEUS).
Bulte, Carolien S E, Slikkerveer, J., Boer, Christa, Meijer, R.I., de Marchi, S.F., Vogel, R., Meijer, Rick I, Gort, Dennis, Kamp, Otto, Bouwman, R Arthur, Vogel, Rolf, Boer, C., Loer, Stephan A, Gort, D., Bouwman, R.A., Bulte, C.S.E., de Marchi, Stefano F., Loer, S.A., Marchi, S.F. de, Slikkerveer, Jeroen, Kamp, O.   +20 more
core   +1 more source

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Michele D'Orazio, Biagio Palmisano, Silvia Franco, Arianna Mencattini, Roberta Angelini, Eugenio Martinelli, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +17 more
wiley   +1 more source

Laser speckle contrast imaging of perfusion in oncological clinical applications: a literature review

Radiology and Oncology
Laser speckle coherence imaging (LSCI) is an emerging imaging modality that enables noninvasive visualization and assessment of tissue perfusion and microcirculation.
Hren Rok, Brezar Simona Kranjc, Marhl Urban, Sersa Gregor   +3 more
doaj   +1 more source

Magnetic resonance imaging of perfusion [PDF]

Magnetic Resonance in Medicine, 1990
AbstractRecent developments have shown that diffusion and blood microcirculation (perfusion) could be imaged and measured noninvasively by MRI. The purpose of this presentation is to overview the different approaches that use B0 field gradients to monitor diffusion / perfusion. The principles of these different methods are discussed together with their
openaire   +3 more sources

Beyond Patient Reported Pain: Perfusion Magnetic Resonance Imaging Demonstrates Reproducible Cerebral Representation of Ongoing Post-Surgical Pain

, 2011
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Matthew A Howard, Steven C R Williams, Khawaja, N, Zelaya, Fernando; id_orcid, Zelaya Fernando, Tara F. Renton, Krause Kristina, Krause, Kristina, Krause, K, Massat Nathalie, Massat, Nathalie, Howard Matthew A., Vennart William, Renton, Tara F, Williams, SCR, Tara F Renton, Zelaya, F, William Vennart, Huggins, JP, Nathalie Massat, Fernando Zelaya, John P Huggins, Vennart, William, Williams, Steven C R; id_orcid, Howard, Matthew A; id_orcid, Nadine Khawaja, Schumann, Gunter, Massat, N, Howard, MA, John P. Huggins, Huggins John P., Schumann, G, Vennart, W, Schumann Gunter, Gunter Schumann, Steven C. R. Williams, Williams Steven C. R., Renton, TF, Renton Tara F., Matthew A. Howard, Kristina Krause, Khawaja Nadine, Huggins, John P, Khawaja, Nadine   +43 more
core   +1 more source

Genipin‐Crosslinked, Silane‐Anchored 3D Tumor–Stroma Microtissues for High‐Content On‐Chip Drug Testing

Advanced Healthcare Materials, EarlyView.
We describe a microfluidic tumor‐stroma co‐culture model, engineered to resist collagen‐hydrogel contraction driven by fibroblast activity. Surface silanization with APTES covalently anchors the matrix to the chip, while Genipin crosslinking progressively increases stiffness and elasticity without harming cells. This supports >10 days of co‐culture and
Doriane Le Manach, Reza Kowsari‐Esfahan, Emilia Reszczyńska, Philippe Nghe, Matthias Nees   +4 more
wiley   +1 more source

Mismatch-based delayed thrombolysis: a meta-analysis [PDF]

, 2010
<p><b>Background and Purpose</b>: Clinical benefit from thrombolysis is reduced as stroke onset to treatment time increases. The use of "mismatch" imaging to identify patients for delayed treatment has face validity and has been used in
Lees, K.R., Mishra, N.K., Donnan, G.A., Furlan, A.J., Hacke, W.   +4 more
core   +1 more source