Results 21 to 30 of about 10,771 (173)
Optical genome mapping for detection of chromosomal aberrations in prenatal diagnosis
Acta Obstetricia et Gynecologica Scandinavica, Volume 102, Issue 8, Page 1053-1062, August 2023., 2023 Optical genome mapping reached 97.8% concordant clinical diagnosis with standard‐of‐care methods for all chromosomal aberrations by a singular testing platform, suggesting that optical genome mapping has the potential to become a promising cytogenetic tool for prenatal diagnosis.Qinxin Zhang, Yan Wang, Yiyun Xu, Ran Zhou, Mingtao Huang, Fengchang Qiao, Lulu Meng, An Liu, Jing Zhou, Li Li, Xiuqing Ji, Zhengfeng Xu, Ping Hu +12 morewiley +1 more sourceAssociation between low fetal fraction in cell‐free DNA screening and fetal chromosomal aberrations: A systematic review and meta‐analysis
Prenatal Diagnosis, Volume 43, Issue 7, Page 838-853, June 2023., 2023 Abstract Objective
To perform a systematic review and meta‐analysis of the available literature on low fetal fraction (LFF) in cell‐free DNA (cfDNA) screening and the risk of fetal chromosomal aberrations. Method
We searched articles published between January 2010 and May 2021 in PubMed and EMBASE databases.Ellis C. Becking, Ewoud Schuit, Sophie M. E. van Baar de Knegt, Erik A. Sistermans, Lidewij Henneman, Mireille N. Bekker, Peter G. Scheffer +6 morewiley +1 more sourcePhoton‐shot‐noise‐limited transient absorption soft X‐ray spectroscopy at the European XFEL
Journal of Synchrotron Radiation, Volume 30, Issue 2, Page 284-300, March 2023., 2023 A beam‐splitting off‐axis zone plate setup to measure transient X‐ray absorption spectroscopy is presented, as implemented at the Spectroscopy and Coherent Scattering instrument at the European X‐ray Free‐Electron Laser.Femtosecond transient soft X‐ray absorption spectroscopy (XAS) is a very promising technique that can be employed at X‐ray free ...Loïc Le Guyader, Andrea Eschenlohr, Martin Beye, William Schlotter, Florian Döring, Cammille Carinan, David Hickin, Naman Agarwal, Christine Boeglin, Uwe Bovensiepen, Jens Buck, Robert Carley, Andrea Castoldi, Alessandro D'Elia, Jan-Torben Delitz, Wajid Ehsan, Robin Engel, Florian Erdinger, Hans Fangohr, Peter Fischer, Carlo Fiorini, Alexander Föhlisch, Luca Gelisio, Michael Gensch, Natalia Gerasimova, Rafael Gort, Karsten Hansen, Steffen Hauf, Manuel Izquierdo, Emmanuelle Jal, Ebad Kamil, Suren Karabekyan, Thomas Kluyver, Tim Laarmann, Tobias Lojewski, David Lomidze, Stefano Maffessanti, Talgat Mamyrbayev, Augusto Marcelli, Laurent Mercadier, Giuseppe Mercurio, Piter S. Miedema, Katharina Ollefs, Kai Rossnagel, Benedikt Rösner, Nico Rothenbach, Andrey Samartsev, Justine Schlappa, Kiana Setoodehnia, Gheorghe Sorin Chiuzbaian, Lea Spieker, Christian Stamm, Francesco Stellato, Simone Techert, Martin Teichmann, Monica Turcato, Benjamin Van Kuiken, Heiko Wende, Alexander Yaroslavtsev, Jun Zhu, Serguei Molodtsov, Christian David, Matteo Porro, Andreas Scherz +63 morewiley +1 more sourceApplying minimally invasive biomarkers of chronic stress across complex ecological contexts
American Journal of Human Biology, Volume 34, Issue 11, November 2022., 2022 Abstract
Chronic stress is both theoretically and methodologically challenging to operationalize through biomarkers. Yet minimally invasive, field‐friendly biomarkers of chronic stress are valuable in research linking biology and culture, seeking to understand differential patterns of human development across ecological contexts, and exploring the ...Jason A. DeCaro, Courtney Helfrechtwiley +1 more sourceMegahertz‐rate ultrafast X‐ray scattering and holographic imaging at the European XFEL
Journal of Synchrotron Radiation, Volume 29, Issue 6, Page 1454-1464, November 2022., 2022 Results from the first megahertz‐repetition‐rate X‐ray scattering experiments at the Spectroscopy and Coherent Scattering (SCS) instrument of the European XFEL are presented.The advent of X‐ray free‐electron lasers (XFELs) has revolutionized fundamental science, from atomic to condensed matter physics, from chemistry to biology, giving researchers ...Nanna Zhou Hagström, Michael Schneider, Nico Kerber, Alexander Yaroslavtsev, Erick Burgos Parra, Marijan Beg, Martin Lang, Christian M. Günther, Boris Seng, Fabian Kammerbauer, Horia Popescu, Matteo Pancaldi, Kumar Neeraj, Debanjan Polley, Rahul Jangid, Stjepan B. Hrkac, Sheena K. K. Patel, Sergei Ovcharenko, Diego Turenne, Dmitriy Ksenzov, Christine Boeglin, Marina Baidakova, Clemens von Korff Schmising, Martin Borchert, Boris Vodungbo, Kai Chen, Chen Luo, Florin Radu, Leonard Müller, Miriam Martínez Flórez, André Philippi-Kobs, Matthias Riepp, Wojciech Roseker, Gerhard Grübel, Robert Carley, Justine Schlappa, Benjamin E. Van Kuiken, Rafael Gort, Laurent Mercadier, Naman Agarwal, Loïc Le Guyader, Giuseppe Mercurio, Martin Teichmann, Jan Torben Delitz, Alexander Reich, Carsten Broers, David Hickin, Carsten Deiter, James Moore, Dimitrios Rompotis, Jinxiong Wang, Daniel Kane, Sandhya Venkatesan, Joachim Meier, Florent Pallas, Tomasz Jezynski, Maximilian Lederer, Djelloul Boukhelef, Janusz Szuba, Krzysztof Wrona, Steffen Hauf, Jun Zhu, Martin Bergemann, Ebad Kamil, Thomas Kluyver, Robert Rosca, Michał Spirzewski, Markus Kuster, Monica Turcato, David Lomidze, Andrey Samartsev, Jan Engelke, Matteo Porro, Stefano Maffessanti, Karsten Hansen, Florian Erdinger, Peter Fischer, Carlo Fiorini, Andrea Castoldi, Massimo Manghisoni, Cornelia Beatrix Wunderer, Eric E. Fullerton, Oleg G. Shpyrko, Christian Gutt, Cecilia Sanchez-Hanke, Hermann A. Dürr, Ezio Iacocca, Hans T. Nembach, Mark W. Keller, Justin M. Shaw, Thomas J. Silva, Roopali Kukreja, Hans Fangohr, Stefan Eisebitt, Mathias Kläui, Nicolas Jaouen, Andreas Scherz, Stefano Bonetti, Emmanuelle Jal +98 morewiley +1 more sourcePump–probe capabilities at the SPB/SFX instrument of the European XFEL
Journal of Synchrotron Radiation, Volume 29, Issue 5, Page 1273-1283, September 2022., 2022 The pump–probe capabilities at the SPB/SFX instrument of the European XFEL are discussed.Pump–probe experiments at X‐ray free‐electron laser (XFEL) facilities are a powerful tool for studying dynamics at ultrafast and longer timescales. Observing the dynamics in diverse scientific cases requires optical laser systems with a wide range of wavelength ...Jayanath C. P. Koliyadu, Romain Letrun, Henry J. Kirkwood, Jia Liu, Man Jiang, Moritz Emons, Richard Bean, Valerio Bellucci, Johan Bielecki, Sarlota Birnsteinova, Raphael de Wijn, Thomas Dietze, Juncheng E, Jan Grünert, Daniel Kane, Chan Kim, Yoonhee Kim, Max Lederer, Bradley Manning, Grant Mills, Luis L. Morillo, Nadja Reimers, Dimitrios Rompotis, Adam Round, Marcin Sikorski, Cedric M. S. Takem, Patrik Vagovič, Sandhya Venkatesan, Jinxiong Wang, Ulrike Wegner, Adrian P. Mancuso, Tokushi Sato +31 morewiley +1 more sourceAD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery
Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 8, Issue 1, 2022., 2022 Abstract Introduction
The portfolio of novel targets to treat Alzheimer's disease (AD) has been enriched by the Accelerating Medicines Partnership Program for Alzheimer's Disease (AMP AD) program. Methods
Publicly available resources, such as literature and databases, enabled a data‐driven effort to identify existing small molecule modulators for many ...Frances M. Potjewyd, Joel K. Annor‐Gyamfi, Jeffrey Aubé, Shaoyou Chu, Ivie L. Conlon, Kevin J. Frankowski, Shiva K. R. Guduru, Brian P. Hardy, Megan D. Hopkins, Chizuru Kinoshita, Dmitri B. Kireev, Emily R. Mason, Charles T. Moerk, Felix Nwogbo, Kenneth H. Pearce, Timothy I. Richardson, David A. Rogers, Disha M. Soni, Michael Stashko, Xiaodong Wang, Carrow Wells, Timothy M. Willson, Stephen V. Frye, Jessica E. Young, Alison D. Axtman +24 morewiley +1 more sourceUse of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology
Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 8, Issue 1, 2022., 2022 Abstract Introduction
A chemogenomic set of small molecules with annotated activities and implicated roles in Alzheimer's disease (AD) called the AD Informer Set was recently developed and made available to the AD research community: https://treatad.org/data‐tools/ad‐informer‐set/. Methods
Small subsets of AD Informer Set compounds were selected for AD‐Frances M. Potjewyd, Joel K. Annor‐Gyamfi, Jeffrey Aubé, Shaoyou Chu, Ivie L. Conlon, Kevin J. Frankowski, Shiva K. R. Guduru, Brian P. Hardy, Megan D. Hopkins, Chizuru Kinoshita, Dmitri B. Kireev, Emily R. Mason, Charles T. Moerk, Felix Nwogbo, Kenneth H. Pearce Jr., Timothy I. Richardson, David A. Rogers, Disha M. Soni, Michael Stashko, Xiaodong Wang, Carrow Wells, Timothy M. Willson, Stephen V. Frye, Jessica E. Young, Alison D. Axtman +24 morewiley +1 more sourcePlanning for a second career
Journal of New Librarianship, 2018
This column details the decision-making process and research that second career librarians conduct as they contemplate a career change.
Paula Pergamentdoaj +1 more source