Results 61 to 70 of about 17,483 (168)

Cellular and molecular cross‐talk in atrial fibrillation: The role of non‐cardiomyocytes in creating an arrhythmogenic substrate

The Journal of Physiology, EarlyView.
Abstract figure legend Illustration of cellular and molecular cross‐talk in atrial fibrillation. Left: a schematic of cardiac tissue showing cardiomyocytes, fibroblasts, adipocytes, inflammatory cells and the coagulation system. Right: direct and indirect cross‐talk between different cell types, with the impact of direct cross‐talk on action potential (
Zhenyu Dong, Ruben Coronel, Joris R. de Groot   +2 more
wiley   +1 more source

Intravenous xenogeneic transplantation of human adipose-derived stem cells improves left ventricular function and microvascular integrity in swine myocardial infarction model [PDF]

, 2015
OBJECTIVES: The potential for beneficial effects of adipose-derived stem cells (ASCs) on myocardial perfusion and left ventricular dysfunction in myocardial ischemia (MI) has not been tested following intravenous delivery.
Bull, Chris, Chen, Peng-Sheng, Deuter-Reinhard, Maja, Feng, Dongni, Hong, Soon Jun, Johnstone, Brian H., Kihlken, John, Kyle, Aaron, Lindner, Jonathan R., March, Keith L., Merfeld-Clauss, Stephanie, Rogers, Pamela I., Traktuev, Dmitry O., Warfel, Jessica, Xie, Jie   +14 more
core   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, Volume 13, Issue 8, 9 February 2026.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Additional file 1 of Relation between quantity and quality of peri-coronary epicardial adipose tissue and its underlying hemodynamically significant coronary stenosis

, 2020
Additional file 1: Figure S1. Study flow-chart. Table S1. Lesion-level predictors for myocardial ischemia in univariate and multivariate analyses.
Du, Yu, Yang, Lin, Liu, Yan, Yang, Bangguo, Lv, Sai, Hu, Chenping, Zhu, Yong, Zhang, Hongkai, Ma, Qian, Wang, Zhijian, Liu, Yuyang, Shi, Dongmei, Zhao, Yingxin, Xu, Lei, Zhou, Yujie   +14 more
openaire   +1 more source

Pericardial Fat and Echocardiographic Measures of Cardiac Abnormalities [PDF]

, 2013
Objective: Pericardial adipose tissue (PAT), a regional fat depot adjacent to the myocardium, may mediate the complex relation between obesity and cardiac left ventricular (LV) abnormalities.
Carr, J. Jeffery, Ding, Jingzhong, Fox, Caroline, Hickson, DeMarc A., Liu, Jiankang, May, Warren L., Taylor, Herman A.   +6 more
core   +1 more source

Changes of Serum CTRP12 in Patients With Coronary Artery Disease After the Treatment of Percutaneous Coronary Intervention and Its Relationship With In‐Stent Restenosis

Clinical Cardiology, Volume 49, Issue 1, January 2026.
Serum CTRP12 levels are significantly lower in CAD patients, and significant correlate to disease severity and dynamic changes after PCI. They may serve as a potential biomarker for diagnosing CAD and predicting ISR occurrence. ABSTRACT Background C1q/tumor necrosis factor‐related protein 12 (CTRP12) plays a protective role in coronary artery disease ...
Botao Zhao, Yuchao Shen
wiley   +1 more source

Morphologic and Morphometric Study of the Heart and Its Great Arteries in the Common Pheasant (Phasianus colchicus)

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
The common pheasant heart is elongated and conical, with thicker left ventricular walls and a complex atrioventricular valve structure. Purkinje fibres show strong desmin but no α‐SMA expression, providing detailed insights into cardiovascular morphology and adaptations in birds, supporting comparative and conservation studies.
Hadis Ramezani, Nader Goodarzi
wiley   +1 more source

Use of coronary artery calcium score and coronary CT angiography to guide cardiovascular prevention and treatment

Therapeutic Advances in Cardiovascular Disease
Currently, cardiovascular risk stratification to guide preventive therapy relies on clinical scores based on cardiovascular risk factors. However, the discriminative power of these scores is relatively modest.
Maria Rita Lima, Pedro M. Lopes, António M. Ferreira   +2 more
doaj   +1 more source

Leptin augments coronary vasoconstriction and smooth muscle proliferation via a Rho kinase dependent pathway [PDF]

, 2016
Leptin has been implicated as a key upstream mediator of pathways associated with coronary vascular dysfunction and disease. The purpose of this investigation was to test the hypothesis that leptin modifies the coronary artery proteome and promotes ...
Goodwill, Adam G., Kiel, Alexander M., Noblet, Jillian N., Sassoon, Daniel J., Tune, Johnathan D.   +4 more
core   +3 more sources

ASSOCIATION OF GHRELIN RECEPTOR AND INFLAMMATION IN PERI-ATRIAL ADIPOSE TISSUE FROM OBESE PATIENTS WITH POSTOPERATIVE ATRIAL FIBRILLATION.

Acta Endocrinologica, 2020
Context Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice. The increasing evidence supports links between inflammation and AF. There is evidence showing that obesity is a major cause of adipose tissue (AT) inflammation.
V. Mocanu, D. Timofte, T. Oboroceanu, I. Cretu-Silivestru, A. Pricope-Veselin, M. Moraru, D. Butcovan   +6 more
semanticscholar   +1 more source