Transcatheter interatrial shunt device for the treatment of heart failure with preserved ejection fraction (REDUCE LAP-HF I [Reduce Elevated Left Atrial Pressure in Patients With Heart Failure]): A phase 2, randomized, sham-controlled trial [PDF]
Background -In non-randomized, open-label studies, a transcatheter interatrial shunt device (IASD, Corvia Medical) was associated with lower pulmonary capillary wedge pressure (PCWP), less symptoms, and greater quality of life and exercise capacity in ...
Basuray, Anupam +17 more
core +1 more source
Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu +12 more
wiley +1 more source
Objective This investigation evaluates Endothelial Cell-Specific Molecule-1 (Endocan), an endothelial-derived protein, for its capacity to discriminate between healthy and pathological peri-implant tissues and its diagnostic potential in peri-implant ...
Ahmed I. Awad +3 more
doaj +1 more source
Diagnóstico e tratamento de doenças peri-implantares: conceitos atuais [PDF]
Dissertação para obtenção do grau de Mestre no Instituto Superior de Ciências da Saúde Egas MonizAtualmente o tratamento com implantes dentários tem-se tornado cada vez mais frequente para repor dentes perdidos, demonstrando taxas de sucesso de 95% após ...
Rodrigues, Jorge Miguel Gaspar
core
Promotion of DFU Wound Healing via BRG1–COL16A1 Axis in Fibroblasts
In normal wound healing, transcription factor BRG1 is upregulated and binds the COL16A1 promoter to enhance its expression, promoting fibroblast proliferation, migration, contraction, extracellular matrix deposition, and granulation tissue formation, thus accelerating wound closure.
Penghui Wang +10 more
wiley +1 more source
Objectives Type 2 diabetes mellitus (T2DM) is a major systemic disease, predisposing patients to inflammatory conditions, and it is considered a grade modifier of periodontitis.
Luca Sbricoli +6 more
doaj +1 more source
A randomized clinical trial about presence of pathogenic microflora and risk of peri-implantitis: comparison of two different types of implant-abutment connections [PDF]
OBJECTIVE: The aim of this in vivo study was to evaluate two different types of implant-abutment connections: screwed connection and cemented connection, analyzing peri-implant bacteria microflora as well as other clinical parameters.
De Angelis, Francesca +5 more
core
Biocompatibility and antibacterial properties of zirconium nitride coating on titanium abutments: An in vitro study [PDF]
Improving soft tissue attachment and reducing bacterial colonization on titanium abutments are key factors for the long-term maintenance of healthy soft and hard peri-implant tissues.
Bressan, Eriberto +7 more
core +2 more sources
Endothelial GPR68 is identified as a critical regulator of collateral artery growth in peripheral artery disease. Genetic and pharmacological evidence demonstrates that GPR68 integrates hemodynamic cues to drive monocyte recruitment and inflammatory remodeling, thereby promoting collateral arteriogenesis and tissue perfusion after ischemia ...
Yiyan Song +12 more
wiley +1 more source
Background Peri-implant crevicular fluid (PICF) contains calprotectin and NTx, which are markers for inflammation and bone resorption, respectively. The aims of this pilot study were to compare calprotectin and NTx levels in PICF from implant sites with ...
Eijiro Sakamoto +5 more
doaj +1 more source

