Results 51 to 60 of about 5,479,081 (206)

Animal models for peri-implant mucositis and peri-implantitis [PDF]

, 2015
The treatment of infectious diseases affecting osseointegrated implants in function has become a demanding issue in implant dentistry. Since the early 1990s, preclinical data from animal studies have provided important insights into the etiology ...
Schwarz, Frank, Engebretson, Steven P, Sculean, Anton, Sager, Martin, Becker, Jürgen   +4 more
core   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

Evaluation of trabecular bone structure using fractal analysis in patients with peri-implant health and disease

BMC Oral Health
Background Peri-implant diseases are associated with inflammatory changes affecting the peri-implant bone; however, objective radiographic markers for assessing trabecular bone structure are limited.
Okan Özen, Vesile Elif Toy, Duygu Çelik Özen   +2 more
doaj   +1 more source

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

Advanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan, Shukui Du, Chunfei Li, Xinjie Li, Shuyang Mu, Anran Qu, Hengxu Yan, Chongchong Xu, Jinnong Yang, Jingkai Sun, Yijun Wang, Jiayang Xiao, Fuyuan Zhang, Linlin Wang, Tiegang Li, Rui Zhao, Dawei Guan   +16 more
wiley   +1 more source

Primary prevention of peri-implantitis: managing peri-implant mucositis [PDF]

, 2015
AIMS Over the past decades, the placement of dental implants has become a routine procedure in the oral rehabilitation of fully and partially edentulous patients. However, the number of patients/implants affected by peri-implant diseases is increasing.
Genco, Robert, Aass, Anne Merete, Salvi, Giovanni Edoardo, Zitzmann, Nicola,, Zitzmann, Nicola U, Giovannoli, Jean Louis, Tomasi, Cristiano, Figuero, Elena, Tomasi, Cristiano,, Schwarz, Frank, Salvi, Giovanni Eduardo, Zitzmann, Nicola, Derks, Jan,, Demirel, Korkud, Berglundh, Tord,, Goldstein, Moshe, Salvi, Giovanni E, Polyzois, Ioannis, Berglundh, Tord, Lambert, France, Serino, Giovanni, Jepsen, Søren, Derks, Jan, Ortiz-Vigon, Alberto, Salvi, Giovanni E., Jepsen, Soren, Zitzmann, Nicola U.   +26 more
core   +2 more sources

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

Advanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English, Dorothea Böken, Matthew W. Cotton, Matthew R. Cheetham, Johanna S. Jackson, Georg Meisl, John S. H. Danial, Paul M. Matthews, Nurun N. Fancy, David Klenerman   +9 more
wiley   +1 more source

Calprotectin and cross-linked N-telopeptides of type I collagen levels in crevicular fluid from implant sites with peri-implant diseases: a pilot study

International Journal of Implant Dentistry, 2018
Background Peri-implant crevicular fluid (PICF) contains calprotectin and NTx, which are markers for inflammation and bone resorption, respectively. The aims of this pilot study were to compare calprotectin and NTx levels in PICF from implant sites with ...
Eijiro Sakamoto, Rie Kido, Yoritoki Tomotake, Yoshihito Naitou, Yuichi Ishida, Jun-ichi Kido   +5 more
doaj   +1 more source

Peri-Implant Health and the Knowing-Doing Gap—A Digital Survey on Procedures and Therapies

Frontiers in Dental Medicine, 2021
Objectives: Peri-implant tissue maintenance and treatment is becoming a serious challenge in implantology. With increasing numbers of implants being placed, more cases of peri-implant mucositis and peri-implantitis is seen.
Badra Hussain, Håvard Jostein Haugen, Anne Merete Aass, Mariano Sanz, Mariano Sanz, Georgios N. Antonoglou, Philippe Bouchard, Philippe Bouchard, Philippe Bouchard, Darko Bozic, Peter Eickholz, Karin Jepsen, Sören Jepsen, Ebru Ozkan Karaca, Bahar Eren Kuru, Carlos E. Nemcovsky, Panos N. Papapanou, Andrea Pilloni, Stefan Renvert, Stefan Renvert, Stefan Renvert, Stefan Renvert, Mario Roccuzzo, Javier Sanz-Esporrin, Axel Spahr, Andreas Stavropoulos, Andreas Stavropoulos, Anders Verket, Domagoj Vražić, Ståle Petter Lyngstadaas   +29 more
doaj   +1 more source

A influência da geometria do implante na perda óssea peri-implantar: um estudo de corte transversal em humanos [PDF]

, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Odontologia, Florianópolis, 2015.Objetivo: O objetivo deste estudo foi verificar a influência da geometria do implante na perda ...
Pereira, Maurício Assunção
core  

Reversing Macrophage Immunometabolic Dysfunction in Prolonged Infections Via a Glutaminolysis‐Fueled Restoration‐Based Hierarchically Selective Therapeutic System

Advanced Science, EarlyView.
A hierarchically selective immunotherapeutic nanoplatform, mGls@HEV‐MTP, selectively restores macrophage immunocompetence through GLS1‐mediated restoration of glutaminolysis‐fueled anaplerosis. Concurrently, it renders Staphylococcus aureus (S. aureus) more readily recognizable to the metabolically reprogrammed macrophages, thereby facilitating ...
Weinan Yang, Zihao An, Honglu Cai, Congsun Li, Jiaxuan Zou, Wushi Cui, Wentao Chen, Tao Zhang, Shicheng Wang, Zizhan Su, Jian Xiao, Tao Sun, Bin Hu, Min Cheng, Zhongru Gou, Jianbin Xu, An Liu, Haobo Wu   +17 more
wiley   +1 more source