Results 31 to 40 of about 62,684 (271)

INSPECT: A Retrospective Study to Evaluate Long-term Effectiveness and Safety of Darvadstrocel in Patients With Perianal Fistulizing Crohn’s Disease Treated in the ADMIRE-CD Trial

Inflammatory Bowel Diseases, 2022
Background The efficacy of a single administration of darvadstrocel (expanded allogeneic adipose-derived mesenchymal stem cells) for treating complex perianal fistulas in patients with Crohn’s disease was demonstrated in a randomized, double-blind trial (
J. Panés, G. Bouma, M. Ferrante, T. Kucharzik, M. Nachury, de Juan Fernando de la Portilla, W. Reinisch, F. Selvaggi, J. Tschmelitsch, N. Brett, M. Ladouceur, M. Binek, G. Hantsbarger, S. Campbell-Hill, C. Karki, C. Buskens   +15 more
semanticscholar   +1 more source

Postoperative Packing of Perianal Abscess Cavities (PPAC2): randomized clinical trial

British Journal of Surgery, 2022
Background Perianal abscess is common. Traditionally, postoperative perianal abscess cavities are managed with internal wound packing, a practice not supported by evidence.
K. Newton, J. Dumville, M. Briggs, J. Law, Julia Martin, L. Pearce, C. Kirwan, T. Pinkney, A. Needham, R. Jackson, S. Winn, H. McCulloch, James O. Hill, A. Watson, M. Johnson, L. Hiller, E. Psarelli, L. Murray, A. Smith, S. Brown, B. Singh, C. Newby, O. Ali, A. Sukha, N. Blencowe, S. Narang, N. Reeves, G. Faulkner, S. Rajamanickam, J. Evans, S. Mangam, M. Harilingham, C. J. Smart, S. J. Ward, M. Bogdan, K. Amin, Z. Al-Khaddar, E. Davies, P. Patel, A. Stearns, I. Shaik, J. Hernon, A. Pal, M. Lewis, J. Barker, A. Gerrard, M. Abdel-Halim, P. Shuttleworth, M. Lee, A. B. P. Peckham-Cooper, A. Hague, C. Challand, C. Steele, N. Fearnhead, S. van Laarhoven, R. Brady, F. Shaban, N. Wong, W. Ngu, G. Williams, R. Codd, D. Magowan, K. Leong, A. Torrance, B. Bharathan, N. Pawa, H. Sekhon, I. Singh, A. Alabi, D. Berry, V. Trompetas, J. Hughes, R. Lunevicius, K. Mann, S. Dixon, T. Ingram, T. Gilbert, C. Brooks, G. Madzamba, A. Pullyblank, G. Dovell, L. Newton, N. Carter, P. May-Miller, S. Shaikh, R. Shearer, C. Macleod, C. Parnaby, A. Abdelmabod, L. Titu, T. Majeed, R. Hargest, J. Parker, C. Zabkiewicz, F. Soliman, G. Gossedge, H. Selvachandran, M. Dilworth, D. Vimalachandran, H. Singh, H. Koh, J. Randall, S. Moug, A. Adeosun, G. Dennison, N. Curtis, N. Smart, S. Duff, M. Rahman, F. Wu   +109 more
semanticscholar   +1 more source

Fistula Perianal [PDF]

, 2023
Fistula perianal merupakan sebuah hubungan yang abnormal antara epitel dari kanalis anal dan epidermis dari kulit perianal. Fistula perianal adalah bentuk kronik dari abses anorektal yang tidak sembuh yang membentuk traktus akibat inflamasi.
Kastiaji , Hendra, Hayati, Zilva
core   +1 more source

PERAWATAN PERIANAL DENGAN BABY OIL MENURUNKAN KEJADIAN DIAPER DERMATITIS PADA NEONATUS DI RUANG NEONATUS RSUD SIDOARJO

Jurnal Ilmiah Kesehatan, 2015
The Influence of Perianal Care with Baby Oil in Order to Prevent Diaper Dermatitis on Neonates in Neonates Room of RSUD Sidoarjo. The purpose of this research is to know the effect of perianal  care with baby oil in order to prevent diaper dermatitis on
Farida Umamah, Navi Fitrothul Chasanah
doaj   +1 more source

Magnetic Resonance Imaging in Giant Perianal Epidermoid

Journal of Gastrointestinal and Abdominal Radiology, 2022
Perianal epidermoid cyst is a rare entity and is commonly diagnosed late owing to its slow-growing nature. Imaging plays a vital role in diagnosis and differentiation from other cysts such as dermoid, tailgut, and rectal duplication cysts.
Aruna Raman Patil, Amit Bansal, Nilotpal Chakma, Ravishankar Bhat, Swarna Shivakumar   +4 more
doaj   +1 more source

Darvadstrocel for Complex Perianal Fistulas in Japanese Adults with Crohn’s Disease: A Phase 3 Study

Journal of Crohn's & Colitis, 2022
Background and Aims Previous studies conducted in Europe suggested that darvadstrocel, a suspension of expanded, allogeneic, adipose-derived, mesenchymal stem cells, is safe and effective for treatment-refractory complex perianal fistulas in patients ...
Satomi Furukawa, T. Mizushima, R. Nakaya, M. Shibata, T. Yamaguchi, Kenji Watanabe, K. Futami   +6 more
semanticscholar   +1 more source

Infantile perianal pyramidal protrusion: a case report with dermoscopy and ultrasound findings

Dermatology Practical & Conceptual, 2015
Infantile perianal pyramidal protrusion, it is a rare benign cutaneous condition described in relatively recent times. It is considered to be under-reported in the pediatric literature because it is often mistaken for other conditions. The unawareness of
Arianna Lamberti, Georgios Filippou, Antonella Adinolfi, Michele Fimiani, Pietro Rubegni   +4 more
doaj   +1 more source

Follow-up Study to Evaluate the Long-term Safety and Efficacy of Darvadstrocel (Mesenchymal Stem Cell Treatment) in Patients With Perianal Fistulizing Crohn’s Disease: ADMIRE-CD Phase 3 Randomized Controlled Trial

Diseases of the Colon & Rectum, 2021
BACKGROUND: Darvadstrocel is an expanded allogeneic adipose-derived mesenchymal stem cell therapy for the treatment of complex perianal fistulas in patients with Crohn’s disease.
D. García-Olmo, I. Gilaberte, M. Binek, A. D'Hoore, D. Lindner, F. Selvaggi, A. Spinelli, J. Panés   +7 more
semanticscholar   +1 more source

Efficacy and Safety of 2 Vedolizumab Intravenous Regimens for Perianal Fistulizing Crohn's Disease: ENTERPRISE Study.

Clinical Gastroenterology and Hepatology, 2021
BACKGROUND & AIMS Fistulizing Crohn's disease (CD) is challenging to treat. We report results from ENTERPRISE, a randomized, double-blind, phase 4 trial, evaluating 2 vedolizumab intravenous dosing regimens in patients with fistulizing CD.
D. A. Schwartz, L. Peyrin-Biroulet, K. Lasch, S. Adsul, S. Danese   +4 more
semanticscholar   +1 more source

Mri Evaluation Of Anal And Perianal Diseases [PDF]

, 2019
Anal and perianal region is a commonly affected area in the course of several inflammatory, infectious, and neoplastic diseases. Several imaging modalities may be used in imaging evaluation of this area and magnetic resonance imaging (MRI) emerges as the
Karcaaltincaba, Musturay, Mustafa Nasuh Özmen, Onur, Mehmet Ruhi, Mehmet Ruhi Onur, Ali Konan, Balci, Sinan, Karaosmanoglu, Ali Devrim, Konan, Ali, Akata, Deniz, Ozmen, Mustafa Nasuh, Ali Devrim Karaosmanoğlu, Sinan Balcı, Deniz Akata, Muşturay Karçaaltıncaba   +13 more
core   +1 more source