Results 51 to 60 of about 62,684 (271)

Cancer in perianal fistulas

, 2013
The presence of a perianal fistula as a complication related to Crohn's disease (CD) was first described by Penner and by Burrill Crohn himself in 1938 [1].
A. Frontali, D. Foschi, Alice Frontali, G. M. Sampietro, Gianluca M. Sampietro, Diego Foschi   +5 more
core   +1 more source

Correlation between Polymorphisms of Vitamin D Metabolism Genes and Perianal Disease in Crohn’s Disease

Biomedicines
Although the role of vitamin D (VD) in the pathogenesis and progression of Crohn’s disease (CD) is known, the association between single-nucleotide polymorphisms (SNPs) of genes linked to vitamin D pathway and CD risk is still under study.
Jessica Cusato, Carla Cafasso, Miriam Antonucci, Alice Palermiti, Alessandra Manca, Gian Paolo Caviglia, Marta Vernero, Angelo Armandi, Giorgio Maria Saracco, Antonio D’Avolio, Davide Giuseppe Ribaldone   +10 more
doaj   +1 more source

The role of MRI in perianal fistulizing disease: diagnostic imaging and classification systems to monitor disease activity

Abdominal Radiology
Perianal fistulizing disease, commonly associated with Crohn’s disease, poses significant diagnostic and therapeutic challenges due to its complex anatomy and high recurrence rates.
J. Arkenbosch, O. van Ruler, A. D. de Vries, C. Janneke van der Woude, R. Dwarkasing   +4 more
semanticscholar   +1 more source

Perianal fistulizing Crohn's disease-associated anorectal and fistula cancers: systematic review and expert consensus.

Clinical Gastroenterology and Hepatology
BACKGROUND AND AIMS Perianal fistulizing Crohn's disease (PFCD)-associated anorectal and fistula cancers are rare but often devastating diagnoses. However, given the low incidence and consequent lack of data and clinical trials in the field, there is ...
S. Wong, C. Rowan, E. D. Brockmans, C. Law, E. Giselbrecht, Celina Ang, S. Khaitov, D. Sachar, L. S. Winata, B. Verstockt, A. Spinelli, David T. Rubin, Parakkal Deepak, D. McGovern, Benjamin D. McDonald, Phillip Lung, L. Lundby, A. Lightner, S. Holubar, L. Hanna, Carla Hamarth, J. Geldof, A. Dige, Benjamin L. Cohen, M. Carvello, C. Bonifacio, G. Bislenghi, Corina Camille Behrenbruch, D. Ballard, E. Altinmakas, Shaji Sebastian, P. Tozer, A. Hart, J. Colombel   +33 more
semanticscholar   +1 more source

Mystery Behind Hidden Long Standing Perianal Fistula-mucinous Adenocarcinoma [PDF]

Mucinous adenocarcinomas (MA) of the perianal region is a rare entity and have an uncertain etiopathogenesis. They are mostly contributed by, or MA arising from chronic perianal fistula (PF) has an indolent growth with locoregional spread, and increased ...
Jeena Sathyan, Govardhan G M, Jyothi K R, Kawari Sowbhagyalaxmi Ramesh, Krishna Prasad Shetty, Sunil Kumar Shetty   +5 more
core   +1 more source

Nicorandil Induced Perianal Ulceration [PDF]

, 2009
Nicorandil is a cardioprotective drug which is used in the prophylaxis and long-term treatment of angina pectoris. Debilitating perianal ulcer is a rare complication of Nicorandil therapy which can cause diagnostic and management dilemmas.
C Angel, W Baraza, J Garner, J P Tiernan, B M Shrestha, W Chelham   +5 more
core   +1 more source

Mesenchymal Stem Cells for Perianal Crohn’s Disease

Cells, 2019
Perianal fistulizing Crohn’s disease (PFCD) is associated with significant morbidity and might negatively impact the quality of life of CD patients.
Michele Carvello, Amy Lightner, Takayuki Yamamoto, Paulo Gustavo Kotze, Antonino Spinelli   +4 more
doaj   +1 more source

Fibrosis and MAGNIFI-CD Activity Index at Magnetic Resonance Imaging to Predict Treatment Outcome in Perianal Fistulizing Crohn’s Disease Patients

Journal of Crohn's & Colitis, 2021
Background and Aims Characteristic magnetic resonance imaging [MRI] features associated with long-term perianal fistula closure are still being discussed.
Kyra L. van Rijn, Elise M. Meima-van Praag, P. Bossuyt, G. D'Haens, K. Gecse, K. Horsthuis, H. J. Snijder, J. Tielbeek, C. Buskens, J. Stoker   +9 more
semanticscholar   +1 more source

Perianal bronchogenic cyst: A report of two cases

Indian Journal of Pathology and Microbiology, 2013
Cutaneous presentations of bronchogenic cysts are rare in all age groups, particularly in adults. Previous reports showed that cutaneous manifestations of bronchogenic cysts were frequently presented above abdominal region. Here we present two cases of a
Liancheng Liu, Yuru Zhang, Zhongtao Zhang, Liying Si   +3 more
doaj   +1 more source

Ustekinumab is effective for perianal fistulising Crohn's disease: a real-world experience and systematic review with meta-analysis

BMJ Open Gastroenterology, 2021
Background Perianal Crohn’s disease (pCD) is a debilitating complication affecting up to 30% of Crohn’s disease (CD) population, leading to increased morbidity, mortality and decreased quality of life. Despite the growing armamentarium of medications for
Gala M. Godoy Brewer, George Salem, M. Afzal, B. Limketkai, Zadid Haq, Maryam Tajamal, J. Melia, M. Lazarev, F. Selaru, A. Parian   +9 more
semanticscholar   +1 more source